Increased prevalence of restless legs syndrome in patients with acromegaly and effects on quality of life assessed by Acro-QoL

Restless legs syndrome (RLS), a neurological sensory-motor disorder characterized by a compelling urge to move the limbs during the night, is a sleep disturbance that impairs quality of life. Prevalence of RLS and consequences on quality of life were investigated in acromegalic patients. Fifty-six p...

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Bibliographic Details
Published in:Pituitary 2011-12, Vol.14 (4), p.328-334
Main Authors: Cannavò, S., Condurso, R., Ragonese, M., Ferraù, F., Alibrandi, A., Aricò, I., Romanello, G., Squadrito, S., Trimarchi, F., Silvestri, R.
Format: Article
Language:English
Subjects:
Acromegaly
Acromegaly - complications
Acromegaly - epidemiology
Adult
Aged
Case-Control Studies
Circadian rhythms
Cohort Studies
Endocrinology
Female
Health Status Indicators
Human Physiology
Humans
Inventories
Leg
Limbs
Male
Medicine
Medicine & Public Health
Middle Aged
Pituitary
Prevalence
Quality of Life
Research Design
restless legs syndrome
Restless Legs Syndrome - complications
Restless Legs Syndrome - epidemiology
Severity of Illness Index
Sleep and wakefulness
Sleep disorders
Sleep Wake Disorders - diagnosis
Sleep Wake Disorders - epidemiology
Sleep Wake Disorders - etiology
Surveys and Questionnaires
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Summary:Restless legs syndrome (RLS), a neurological sensory-motor disorder characterized by a compelling urge to move the limbs during the night, is a sleep disturbance that impairs quality of life. Prevalence of RLS and consequences on quality of life were investigated in acromegalic patients. Fifty-six patients (20 men, 55.0 ± 1.6 years), 22 with active acromegaly ( group 1 ) and 34 with controlled disease ( group 2 ), and 95 controls (35 men, 52.9 ± 1.1 years) were evaluated by a structured sleep interview concerning insomnia, circadian sleep disorders and excessive diurnal sleepiness (EDS). The Epworth Sleepiness Scale (ESS) questionnaire was administered to those reporting EDS. Patients were investigated by RLS diagnostic interview and International Restless Leg Syndrome — Rating Scale (IRLS-RS). Quality of life was investigated by AcroQoL questionnaire. RLS was diagnosed in 21% of acromegalics and in 4% of controls ( P  
ISSN:1386-341X
1573-7403
DOI:10.1007/s11102-011-0298-z