Optic neuropathy as a presenting feature of systemic lupus erythematosus: two case reports and literature review

Systemic lupus erythematosus (SLE) may affect the eyes and/or visual system in up to a third of patients; however, optic nerve involvement has been rarely reported. SLE presenting as optic neuropathy is exceptional. We report two new cases of optic neuropathy as a presenting feature of SLE. The firs...

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Bibliographic Details
Published in:Lupus 2011-10, Vol.20 (11), p.1214-1218
Main Authors: Frigui, M, Frikha, F, Sellemi, D, Chouayakh, F, Feki, J, Bahloul, Z
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Adult
Antibodies, Antiphospholipid - blood
antiphospholipid antibodies
Case reports
Female
Humans
Ischemia
Literature reviews
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - diagnosis
Lupus Erythematosus, Systemic - immunology
Male
Optic nerve
Optic Nerve Diseases - diagnosis
Optic Nerve Diseases - drug therapy
Optic Nerve Diseases - etiology
Optic neuritis
Optic Neuritis - etiology
Optic neuropathy
Optic Neuropathy, Ischemic - etiology
Prognosis
Systemic lupus erythematosus
Visual system
Young Adult
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Summary:Systemic lupus erythematosus (SLE) may affect the eyes and/or visual system in up to a third of patients; however, optic nerve involvement has been rarely reported. SLE presenting as optic neuropathy is exceptional. We report two new cases of optic neuropathy as a presenting feature of SLE. The first patient presented with an ischemic optic neuropathy and antiphospholipid antibodies, and the second presented with optic neuritis. A literature review for previous cases of SLE presenting as optic neuropathy was performed. Early diagnosis of SLE-associated optic neuropathy is warranted and leads to a better prognosis.
ISSN:0961-2033
1477-0962
DOI:10.1177/0961203311403344