formal scheme of adsorptional receptors in Pseudomonas aeruginosa and possibilities for its practical implementation

• Published in: Russian journal of genetics 2009, Vol.45 (1), p.35-40
• Main Authors: Pleteneva, E. A, Shaburova, O. V, Krylov, V. N
• Format: Article
• Language: English
• Subjects: Animal Genetics and Genomics; Biomedical and Life Sciences; Biomedicine; Genetics of Microorganisms; Human Genetics; Microbial Genetics and Genomics; Pseudomonas aeruginosa
• ISSN: 1022-7954; 1608-3369
• DOI: 10.1134/S1022795409010050

In recent years, a revival of interest to study of bacteriophages has been observed. Bacteriophages and phage-coded products can be used instead of antibiotics in the treatment of some human and animal infections caused by antibiotic-resistant bacterial strains. Bacteriophages may serve as an excellent method for monitoring anthropogenic changes in bacterial communities, which are connected with the contamination by industrial sewages or infection of water reservoirs with pathogenic bacteria. Technical applicability of bacteriophages may be successful for combating bacterial biofilms, for example, in pipelines. And finally, comparative basic and systemic genomic studies of bacteriophages belonging to various bacterial species are conclusive in understanding and assessing their role in the joint evolution (coevolution) with host bacteria; particularly, this research is important for elucidating mechanisms of phage participation in the horizontal exchange of genetic modules. Possibly, these studies may be useful for the prediction of not only the direction of coevolution of certain bacterial species and their phages but also the time of new pathogenic bacteria origination.