Dyslipidemias in type 2 diabetes mellitus patients in Nnewi South-East Nigeria

• Published in: Annals of African medicine 2011-10, Vol.10 (4), p.285-289
• Main Authors: Jisieike-Onuigbo, N N, Unuigbe, E I, Oguejiofor, C O
• Format: Article
• Language: English
• Subjects: Cardiovascular disease; Cardiovascular diseases; Chi-Square Distribution; Cholesterol; Cholesterol, HDL - blood; Complications and side effects; Control; Cross-Sectional Studies; Diabetes; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - mortality; Diabetes Mellitus, Type 2 - pathology; Disease Progression; Dyslipidemias; Dyslipidemias - epidemiology; Dyslipidemias - mortality; Dyslipidemias - pathology; Female; Hospitals, Teaching; Humans; Hypertriglyceridemia - epidemiology; Hypertriglyceridemia - mortality; Hypertriglyceridemia - pathology; Insulin resistance; Lipids; Male; Middle Aged; Nigeria - epidemiology; Patient outcomes; Prevalence; Risk Assessment; Risk factors; Type 2 diabetes
• ISSN: 1596-3519; 0975-5764
• DOI: 10.4103/1596-3519.87045

Dyslipidemia has been noted to play an integral role in the pathogenesis and progression of micro and macrovascular complications in diabetes mellitus patients. The complications exemplified by renal vascular and cardiovascular disease cause the most morbidity and mortality in this group of patients. This study is aimed at understanding the pattern of dyslipidemia among type 2 diabetic patients. A total of 108 consenting adult type 2 diabetic patients seen in the medical unit of the Nnamdi Azikiwe University Teaching Hospital Nnewi were evaluated in this crosssectional study. Their fasting lipid profile, fasting blood glucose, weight, height and blood pressure were evaluated. The prevalence of dyslipidemia (at least one abnormal lipid profile) was 90.7%. The 24.1% had single dyslipidemia while 66.6% had combined dyslipidemia. Reduced HDL constituted the highest single abnormality (62%) followed by hypertriglyceridemia (56.5%), hypercholesterolemia (53.7%) and high LDL in (44.4%). The duration of DM was not significantly associated with dyslipidemia (P > 0.05). Dyslipidemia is highly prevalent among type 2 diabetic patients in Nigeria with the majority of the patients having combined dyslipidemia. We recommend that aggressive treatment of lipidemia and hyperglycemia can be instituted to reduce the risk of macro and microvascular complications.