Efficacy of dual vaccination of pandemic H1N1 2009 influenza and seasonal influenza on institutionalized elderly: A one-year prospective cohort study

Highlights► Dual vaccination of seasonal influenza and H1N1 2009 in institutionalized elderly. ► Functional status and comorbidity assessed to minimize healthy vaccine bias. ► Dual vaccination was better than vaccination of seasonal influenza alone. ► Reduce all cause mortality and hospitalization b...

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Bibliographic Details
Published in:Vaccine 2011-10, Vol.29 (44), p.7773-7778
Main Authors: Chan, T.C, Hung, I.F.N, Luk, J.K.H, Shea, Y.F, Chan, F.H.W, Woo, P.C.Y, Chu, L.W
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Allergy and Immunology
Applied microbiology
Biological and medical sciences
Cohort Studies
confidence interval
Efficacy
elderly
Female
females
fever
Fundamental and applied biological sciences. Psychology
Hong Kong
Hospitalization
Hospitalization - statistics & numerical data
Hospitals
Humans
Influenza
Influenza A (H1N1) 2009
Influenza Vaccines - administration & dosage
Influenza Vaccines - immunology
Influenza, Human - mortality
Influenza, Human - prevention & control
Institutionalization
Institutionalized elderly
Male
Microbiology
Miscellaneous
Mortality
multivariate analysis
nursing homes
Older people
pandemic
people
pneumonia
Prospective Studies
Survival Analysis
Treatment Outcome
Vaccination
Vaccination - methods
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Virology
World Health Organization
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Summary:Highlights► Dual vaccination of seasonal influenza and H1N1 2009 in institutionalized elderly. ► Functional status and comorbidity assessed to minimize healthy vaccine bias. ► Dual vaccination was better than vaccination of seasonal influenza alone. ► Reduce all cause mortality and hospitalization by dual vaccination.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.07.112