Wearable Defibrillator in Congenital Structural Heart Disease and Inherited Arrhythmias

Patients with congenital structural heart disease (CSHD) and inherited arrhythmias (IAs) are at high risk of ventricular tachyarrhythmias and sudden cardiac death. The present study was designed to evaluate the short- and long-term outcomes of patients with CSHD and IA who received a wearable cardio...

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Bibliographic Details
Published in:The American journal of cardiology 2011-12, Vol.108 (11), p.1632-1638
Main Authors: Rao, Mohan, MD, Goldenberg, Ilan, MD, Moss, Arthur J., MD, Klein, Helmut, MD, Huang, David T., MD, Bianco, Nicole R., PhD, Szymkiewicz, Steven J., MD, Zareba, Wojciech, MD, Brenyo, Andrew, MD, Buber, Jonathan, MD, Barsheshet, Alon, MD
Format: Article
Language:English
Subjects:
Adult
Arrhythmias, Cardiac - genetics
Arrhythmias, Cardiac - mortality
Arrhythmias, Cardiac - therapy
Biological and medical sciences
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Death, Sudden, Cardiac - epidemiology
Death, Sudden, Cardiac - prevention & control
Defibrillators
Equipment Design
Female
Follow-Up Studies
Heart
Heart Defects, Congenital - mortality
Heart Defects, Congenital - physiopathology
Heart Defects, Congenital - therapy
Humans
Incidence
Male
Medical sciences
Mortality
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Retrospective Studies
Risk Factors
Survival analysis
Survival Rate - trends
Time Factors
Treatment Outcome
United States - epidemiology
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Description
Summary:Patients with congenital structural heart disease (CSHD) and inherited arrhythmias (IAs) are at high risk of ventricular tachyarrhythmias and sudden cardiac death. The present study was designed to evaluate the short- and long-term outcomes of patients with CSHD and IA who received a wearable cardioverter-defibrillator (WCD) for the prevention of sudden cardiac death. The study population included 162 patients with CSHD (n = 43) and IA (n = 119) who were prospectively followed up in a nationwide registry from 2005 to 2010. The mortality rates were compared using Kaplan-Meier survival analysis. The mean age of the study patients was 38 ± 27 years. The patients with CSHD had a greater frequency of left ventricular dysfunction (ejection fraction
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2011.07.021