Wrinkles in the Atrium: Age, Atrial Fibrillation, or Something Else

If we consider the 3 main explanations for fibrosis in the atrium--namely, resulting from AF, part of the aging process, and causing AF--and the fact that AF determination on the basis of invasive studies is likely not a RA phenomenon, and this study shows the lack of association with age, then AF g...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2011-11, Vol.58 (21), p.2233-2235
Main Authors: Asirvatham, Samuel J., Gard, Joseph J.
Format: Article
Language:English
Subjects:
Age
Aging
atrial fibrillation
Atrial Fibrillation - complications
Cardiac arrhythmia
Cardiology
Female
fibrosis
Heart Atria - pathology
Humans
Male
NMR
Nuclear magnetic resonance
radiofrequency ablation
Studies
Online Access:Get full text
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Summary:If we consider the 3 main explanations for fibrosis in the atrium--namely, resulting from AF, part of the aging process, and causing AF--and the fact that AF determination on the basis of invasive studies is likely not a RA phenomenon, and this study shows the lack of association with age, then AF giving rise to fibrosis remains a causative role. Diastolic dysfunction leads to an increase in atrial pressures and size, and presumably will promote fibrosis and possibly the persistent forms of AF.\n A specific P-wave morphology suggested interatrial block in patients in whom AF developed, whereas terminal P-wave abnormalities represented delayed conduction into the PVs and did not differ between patients with paroxysmal AF remaining in sinus rhythm and those with new onset AF.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2011.06.060