Association between social isolation and inflammatory markers in depressed and non-depressed individuals: Results from the MONICA/KORA study

Highlight ► Depressed mood and social isolation in combination are associated with raised CRP and IL-6 in men, implying a synergistic effect on inflammation.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2011-11, Vol.25 (8), p.1701-1707
Main Authors: Häfner, S, Emeny, R.T, Lacruz, M.E, Baumert, J, Herder, C, Koenig, W, Thorand, B, Ladwig, K.H
Format: Article
Language:English
Subjects:
Affect
Aged
Allergy and Immunology
Biomarkers - metabolism
C-Reactive Protein - metabolism
Chronic Disease
Combination of depressed mood and social isolation
CRP
Depressed mood
Depression - metabolism
Female
Humans
IL-6
Inflammation - metabolism
Inflammatory response
Interleukin-6 - metabolism
Linear Models
Male
Men
Middle Aged
Population
Psychiatry
Sex Characteristics
Social Environment
Social isolation
Social Isolation - psychology
Stress, Psychological - metabolism
Stress, Psychological - psychology
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Description
Summary:Highlight ► Depressed mood and social isolation in combination are associated with raised CRP and IL-6 in men, implying a synergistic effect on inflammation.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2011.06.017