The usefulness of Tc-99m-MDP bone scintigraphy in detection of articular involvement of Behçet's disease

Articular involvement was reported to be present in approximately 5-76% of Behçet patients. Therefore, we need a useful non-invasive method to detect articular involvement early in Behçet patients with nonspecific complaints. We aimed to evaluate the usefulness of 99mTc-methylene diphosphonate (Tc-9...

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Bibliographic Details
Published in:Annals of nuclear medicine 2006-12, Vol.20 (10), p.649-653
Main Authors: Sahin, Mehmet, Yildiz, Mustafa, Tunc, Sevket Ercan, Cerci, Sureyya, Suslu, Harun, Cure, Erkan, Kutlucan, Ali
Format: Article
Language:English
Subjects:
Adult
Arthritis - diagnostic imaging
Behcet Syndrome - diagnostic imaging
Cartilage, Articular - diagnostic imaging
Female
Humans
Male
Osteochondritis - diagnostic imaging
Radionuclide Imaging
Radiopharmaceuticals
Reproducibility of Results
Sensitivity and Specificity
Sports injuries
Technetium Tc 99m Medronate
Whole Body Imaging - methods
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Summary:Articular involvement was reported to be present in approximately 5-76% of Behçet patients. Therefore, we need a useful non-invasive method to detect articular involvement early in Behçet patients with nonspecific complaints. We aimed to evaluate the usefulness of 99mTc-methylene diphosphonate (Tc-99m-MDP) bone scintigraphy in the detection of the articular involvement of Behçet's disease (BD). Bone scintigraphy with Tc-99m-MDP was performed in 32 (17 male, 15 female) consecutive patients with BD. The sacroiliac (SI) joints with SI index higher than 1.34 were diagnosed as having sacroiliitis. Although joint complaints were present in only 8 (25%) patients, we detected joint involvement by scintigraphy in 27/32 (84.4%) Behçet patients mostly affecting the knees (62.5%), ankles (59.4%), SI joints (25%), wrists (21.9%), shoulders (18.7%), elbows (12.5%) and hips (3.1%). The articular involvement was monoarticular in four cases (12.5%) and was oligoarticular in the remaining. There was no correlation between joint involvement and age, gender, disease duration, drug usage or other clinical manifestations. Despite the fact that our patients were clinically asymptomatic and had normal pelvis radiography, sacroiliitis was found in 8 patients (25%). Bone scintigraphy is sensitive in the diagnosis of joint involvement allowing earlier diagnosis and showing the presence of articular involvement, especially in SI joints.
ISSN:0914-7187
1864-6433
DOI:10.1007/BF02984675