Analysis and Recognition of Erythroid-Specific Gene Promoters Basing on Degenerate Oligonucleotide Motifs

We developed a method to search for degenerate oligonucleotide motifs specific for certain regions in eukaryotic gene promoters. A procedure of promoter recognition based on these motifs is presented. The methods are integrated within the program package ARGO available for Internet users (http://www...

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Bibliographic Details
Published in:Molecular biology (New York) 2001-11, Vol.35 (6), p.833-840
Main Authors: Vishnevsky, O V, Vityaev, E E
Format: Article
Language:English
Subjects:
Eukaryotes
Genomics
Molecular biology
Online Access:Get full text
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Summary:We developed a method to search for degenerate oligonucleotide motifs specific for certain regions in eukaryotic gene promoters. A procedure of promoter recognition based on these motifs is presented. The methods are integrated within the program package ARGO available for Internet users (http://wwwmgs.bionet.nsc.ru/mgs/programs/argo). This method was applied to study erythroid-specific gene promoters. High efficiency of their recognition is demonstrated.[PUBLICATION ABSTRACT]
ISSN:0026-8933
1608-3245
DOI:10.1023/A:1013230117035