Altered calcium homeostasis is correlated with the presence of metabolic syndrome and diabetes in middle-aged and elderly Korean subjects: The Chungju Metabolic Disease Cohort study (CMC study)

Abstract Objective To clarify the association of serum calcium level with metabolic syndrome (MetS) and diabetes in middle-aged and elderly Korean subjects. Design and patients We conducted a population-based, cross-sectional survey of 1329 participants aged over 40 years (median age 65.8) in a rura...

Full description

Saved in:
Bibliographic Details
Published in:Atherosclerosis 2010-10, Vol.212 (2), p.674-681
Main Authors: Kim, Mee Kyoung, Kim, Guilsun, Jang, Eun Hee, Kwon, Hyuk Sang, Baek, Ki Hyun, Oh, Ki Won, Lee, Jin Hee, Yoon, Kun-Ho, Lee, Won Chul, Lee, Kang Woo, Son, Ho Young, Kang, Moo Il
Format: Article
Language:English
Subjects:
Aged
Albumins
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Calcium - metabolism
Cardiology. Vascular system
Cardiovascular
Cardiovascular system
Cohort Studies
Cross-Sectional Studies
Diabetes
Diabetes Mellitus - blood
Diabetes Mellitus - epidemiology
Female
Humans
Korea
Male
Medical sciences
Metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - epidemiology
Middle Aged
Odds Ratio
Pharmacology. Drug treatments
Prevalence
Risk
Serum calcium
Vasodilator agents. Cerebral vasodilators
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objective To clarify the association of serum calcium level with metabolic syndrome (MetS) and diabetes in middle-aged and elderly Korean subjects. Design and patients We conducted a population-based, cross-sectional survey of 1329 participants aged over 40 years (median age 65.8) in a rural area of Chungju, Korea, in 2007. Measurements Serum level of albumin, calcium, 25-hydroxy-vitamin D and intact parathyroid hormone were measured in a central laboratory. Results The prevalence of MetS increased progressively with elevated serum albumin-corrected calcium levels ( P < 0.001 for trend). After adjusting for various covariates, subjects in the highest quintile group (2.45–2.99 mmol/L) compared with the lowest quintile group (2.05–2.24 mmol/L) of serum calcium levels had an odds ratio (OR) for having MetS of 3.11 (95% confidence intervals, CI, 1.95–4.97; P for trend
ISSN:0021-9150
1879-1484
DOI:10.1016/j.atherosclerosis.2010.07.005