Clinical outcomes and virology of equine influenza in a naïve population and in horses infected soon after receiving one dose of vaccine

As part of the control measures of the equine influenza (EI) outbreak, in addition to the strategic use of vaccination to provide buffer zones around infected populations, approval was obtained to vaccinate Thoroughbred racing horses. We review the clinical expression of the disease and virus excret...

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Bibliographic Details
Published in:Australian veterinary journal 2011-07, Vol.89 (s1), p.139-142
Main Authors: Kannegieter, NJ, Frogley, A, Crispe, E, Kirkland, PD
Format: Article
Language:English
Subjects:
Animals
Antibodies, Viral - blood
Disease Outbreaks - veterinary
emergency animal disease
equine influenza
Horse Diseases - epidemiology
Horse Diseases - immunology
Horse Diseases - prevention & control
Horse Diseases - virology
Horses
Influenza A Virus, H3N8 Subtype - genetics
Influenza A Virus, H3N8 Subtype - immunology
Influenza Vaccines - administration & dosage
New South Wales - epidemiology
Orthomyxoviridae Infections - epidemiology
Orthomyxoviridae Infections - immunology
Orthomyxoviridae Infections - veterinary
Orthomyxoviridae Infections - virology
Reverse Transcriptase Polymerase Chain Reaction - veterinary
RNA, Viral - chemistry
RNA, Viral - genetics
Seroepidemiologic Studies
vaccination
Viral Load - veterinary
virology
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Summary:As part of the control measures of the equine influenza (EI) outbreak, in addition to the strategic use of vaccination to provide buffer zones around infected populations, approval was obtained to vaccinate Thoroughbred racing horses. We review the clinical expression of the disease and virus excretion in a population of racehorses that were exposed to EI approximately 7 days after administration of a single dose of the canarypox‐vectored recombinant compared with a similar unvaccinated population of horses at a nearby racetrack. Although this study was undertaken opportunistically and under the difficult field conditions that prevailed during the outbreak, our observations demonstrate that an appropriate vaccine can be effectively used as a disease control measure, even in the face of an outbreak, and therefore should be rapidly implemented as soon as there is evidence of infection in a naïve population.
ISSN:0005-0423
1751-0813
DOI:10.1111/j.1751-0813.2011.00768.x