Cell Size: Chromosomes Get Slapped by a Midzone Ruler

Spatial and temporal coordination of mitotic events has been generally attributed to the coincidental outcome of increasing cyclin-dependent kinase activity. A recent study reports that mitotic events and structures previously considered to be independently controlled are capable of trans-regulation...

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Bibliographic Details
Published in:Current biology 2011-05, Vol.21 (10), p.R388-R390
Main Authors: Ladouceur, Anne-Marie, Ranjan, Rajesh, Maddox, Paul S.
Format: Article
Language:English
Subjects:
Cell Size
Chromosome Segregation - physiology
chromosomes
cyclin-dependent kinase
enzyme activity
genome
Genomic Instability - physiology
mitosis
Mitosis - physiology
Nucleic Acid Conformation
Saccharomycetales
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Summary:Spatial and temporal coordination of mitotic events has been generally attributed to the coincidental outcome of increasing cyclin-dependent kinase activity. A recent study reports that mitotic events and structures previously considered to be independently controlled are capable of trans-regulation to ensure genomic integrity.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2011.04.009