Synthesis and antibacterial and antifungal activity of 2-thiocyanato-2-methyl-3-arylpropionic acid allyl esters

Allyl esters of 2-thiocyanato-2-methyl-3-arylpropionic acids exhibit pronounced antibacterial activity with respect to various test strains of staphylococci, colon bacilli, aerobic bacilli, and yeast fungi. The maximum activity is observed for compounds containing chlorine or bromine atoms at the ar...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2007-11, Vol.41 (11), p.594-595
Main Authors: Grishchuk, B. D., Klimnyuk, S. I., Simchak, R. V., Pokryshko, O. V., Baranovskii, V. S., Gorbovoi, P. M.
Format: Article
Language:English
Subjects:
Antibacterial activity
Antifungal activity
Aromatics
Bacilli
Chlorine
Colon
Esters
Fungi
Nuclei
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Summary:Allyl esters of 2-thiocyanato-2-methyl-3-arylpropionic acids exhibit pronounced antibacterial activity with respect to various test strains of staphylococci, colon bacilli, aerobic bacilli, and yeast fungi. The maximum activity is observed for compounds containing chlorine or bromine atoms at the aromatic nucleus.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-008-0026-9