Synthesis and antimicrobial activity of poly(N-methyl-4-vinylpyridinium triiodide)

Alkylation of poly(4-vinylpyridine) with methyl iodide for 12 h led to synthesis of the anionite poly(N-methyl-4-vinylpyridinium iodide). Iodination of an aqueous solution of the reaction product with an equimolar quantity of iodine in ethanol produced poly(N-methyl-4-vinylpyridinium triiodide) at q...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2010-06, Vol.44 (2), p.61-63
Main Authors: Chernov’yants, M. S., Burykin, I. V., Pisanov, R. V., Shalu, O. A.
Format: Article
Language:English
Subjects:
Ion exchange resins
Medicine
Nuclear magnetic resonance spectroscopy
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:Alkylation of poly(4-vinylpyridine) with methyl iodide for 12 h led to synthesis of the anionite poly(N-methyl-4-vinylpyridinium iodide). Iodination of an aqueous solution of the reaction product with an equimolar quantity of iodine in ethanol produced poly(N-methyl-4-vinylpyridinium triiodide) at quantitative yield. The structure of this compound was confirmed by UV, IR, and 1 H NMR spectroscopy and potentiometric titration. The antimicrobial activities of the compounds synthesized here are presented.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-010-0398-5