MAGE-A family: Attractive targets for cancer immunotherapy

Highlights ► We described the expression and activation mechanism of MAGE-As in cancer. ► We summarized the biological functions of MAGE-As in human tumorigenesis. ► We summarized what is known of the cancer immunotherapy targeting MAGE-A family.

Saved in:
Bibliographic Details
Published in:Vaccine 2011-11, Vol.29 (47), p.8496-8500
Main Authors: Sang, Meixiang, Lian, Yishui, Zhou, Xinliang, Shan, Baoen
Format: Article
Language:English
Subjects:
adults
Allergy and Immunology
Antigens
Applied microbiology
Biological and medical sciences
Breast cancer
Cancer immunotherapy
Cancer Vaccines - administration & dosage
Cancer Vaccines - immunology
Cancer/testis antigens
Cell cycle
Chromosomes
DNA methylation
Epigenetics
Fundamental and applied biological sciences. Psychology
Gene expression
Gene Expression Profiling
genes
germ cells
Humans
Immunization
Immunotherapy
Immunotherapy - methods
MAGE-A
Medical sciences
Melanoma
Melanoma-Specific Antigens - immunology
Melanoma-Specific Antigens - metabolism
Microbiology
neoplasms
Neoplasms - therapy
Peptides
Proteins
Skin cancer
Studies
testes
Tumors
vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights ► We described the expression and activation mechanism of MAGE-As in cancer. ► We summarized the biological functions of MAGE-As in human tumorigenesis. ► We summarized what is known of the cancer immunotherapy targeting MAGE-A family.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.09.014