Synthesis and antibacterial activity of 2-hydrazino5-bromomethyl-4,5-dihydrothiazole hydrazones

A series of 2-hydrazino-5-bromomethyl-4,5-dihydrothiazole hydrazones based on substituted N 4 -allylthiosemicarbazones was synthesized. Some of these hydrazones were found to have moderate antibacterial activity against Staphylococcus aureus 209P, 1 and Shigella flexneri .

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2011-04, Vol.45 (1), p.26-29
Main Authors: Iradyan, M. A., Aroyan, R. A., Avakimyan, D. A., Stepanyan, G. M.
Format: Article
Language:English
Subjects:
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Shigella flexneri
Staphylococcus aureus
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Description
Summary:A series of 2-hydrazino-5-bromomethyl-4,5-dihydrothiazole hydrazones based on substituted N 4 -allylthiosemicarbazones was synthesized. Some of these hydrazones were found to have moderate antibacterial activity against Staphylococcus aureus 209P, 1 and Shigella flexneri .
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-011-0554-6