Intra-abdominal metastasis of an intracranial germinoma via ventriculo-peritoneal shunt in a 13-year-old female

A 13-year-old patient presented with massive intra-abdominal metastasis and spontaneous acute tumour lysis syndrome, 17-months after VP shunt placement for metastatic pineal germinoma treated with cranio-spinal-irradiation. Hyperhydration/rasburicase improved renal function, allowing chemotherapy wi...

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Bibliographic Details
Published in:British journal of neurosurgery 2011-12, Vol.25 (6), p.747-749
Main Authors: Murray, Matthew J., Metayer, Lucy E., Mallucci, Conor L., Hale, Juliet P., Nicholson, James C., Kirollos, Ramez W., Burke, G. A. Amos
Format: Article
Language:English
Subjects:
Abdominal Neoplasms - diagnosis
Abdominal Neoplasms - drug therapy
Abdominal Neoplasms - secondary
Adolescent
Antineoplastic Agents - administration & dosage
Ascites - etiology
Brain Neoplasms - diagnosis
Brain Neoplasms - pathology
Brain Neoplasms - radiotherapy
Brain Neoplasms - surgery
Chemotherapy
Female
Germinoma - diagnosis
Germinoma - radiotherapy
Germinoma - secondary
Germinoma - surgery
Humans
Magnetic Resonance Imaging
Metastasis
Neoplasm Seeding
Neurosurgery
Pinealoma - diagnosis
Pinealoma - radiotherapy
Pinealoma - secondary
Pinealoma - surgery
Tumor Lysis Syndrome - diagnosis
Tumor Lysis Syndrome - metabolism
Tumor Lysis Syndrome - therapy
Tumors
Ventriculoperitoneal Shunt - adverse effects
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Description
Summary:A 13-year-old patient presented with massive intra-abdominal metastasis and spontaneous acute tumour lysis syndrome, 17-months after VP shunt placement for metastatic pineal germinoma treated with cranio-spinal-irradiation. Hyperhydration/rasburicase improved renal function, allowing chemotherapy with subsequent surgery. The patient remains event-free 34-months later. Risk of intra-abdominal metastasis from VP shunts is discussed.
ISSN:0268-8697
1360-046X
DOI:10.3109/02688697.2011.566383