Molecular characterization of Theileria orientalis causing fatal infection in crossbred adult bovines of South India

Abstract The disease condition attributed to have been caused by Theileria orientalis is generally benign. However, it is also thought that the parasite, at least some strains of it, can cause fatal disease. The present communication deals with the clinical signs, postmortem lesions and diagnosis of...

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Bibliographic Details
Published in:Parasitology international 2011-12, Vol.60 (4), p.524-529
Main Authors: Aparna, M, Ravindran, Reghu, Vimalkumar, M.B, Lakshmanan, Bindu, Rameshkumar, P, Kumar, K.G. Ajith, Promod, K, Ajithkumar, S, Ravishankar, Chintu, Devada, K, Subramanian, H, George, Ajith Jacob, Ghosh, S
Format: Article
Language:English
Subjects:
abomasum
adults
Animals
Base Sequence
blood
body temperature
Bovines
Cattle
Cattle Diseases - blood
Cattle Diseases - diagnosis
Cattle Diseases - mortality
Cattle Diseases - parasitology
Cattle Diseases - transmission
crossbreds
Crosses, Genetic
DNA Fingerprinting
DNA, Protozoan - analysis
DNA, Protozoan - genetics
edema
Gastroenterology and Hepatology
genes
Genes, Protozoan
hemorrhage
India - epidemiology
Indonesia
Infectious Disease
lymph nodes
Molecular Sequence Data
Mortality
nose
parasites
parasitology
Phylogeny
Polymerase Chain Reaction
Prevalence
South India
spleen
Survival Rate
Thailand
Theileria
Theileria - classification
Theileria - genetics
Theileria - isolation & purification
Theileria orientalis
Theileriasis - blood
Theileriasis - diagnosis
Theileriasis - mortality
Theileriasis - parasitology
Theileriasis - transmission
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Summary:Abstract The disease condition attributed to have been caused by Theileria orientalis is generally benign. However, it is also thought that the parasite, at least some strains of it, can cause fatal disease. The present communication deals with the clinical signs, postmortem lesions and diagnosis of a fatal disease due to T. orientalis which caused mortality in crossbred adult bovines of South India. High body temperature, lacrimation, nasal discharge, swollen lymph nodes and haemoglobinuria were the symptoms observed. The postmortem lesions observed were punched out ulcers in abomasum, enlargement of spleen, massive pulmonary oedema, frothy exudates in trachea, epicardial and endocardial haemorrhage and haemorrhagic duodenitis. Peripheral blood smear examination revealed rod shaped Theileria sp. organisms. Polymerase chain reaction that amplify the T. orientalis specific P32/33 gene, followed by cloning and sequencing, revealed maximum homology with Narathiwat (Thailand) and Jingole –1 (Indonesia) isolates which were positioned as isolate type 7 of T. orientalis.
ISSN:1383-5769
1873-0329
DOI:10.1016/j.parint.2011.08.002