Impaired Lung Function After Intubation and Mechanical Ventilation for Surgical Ligation of the Ductus Arteriosus in Preterm Infants

Objective Significant patent ductus arteriosus (PDA) in the preterm infant has been associated with pulmonary edema and impaired gas exchange. Therefore, surgical ligature of the DA may be required. However, the effects of intubation and mechanical ventilation on the PDA-induced lung dysfunction pre...

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Bibliographic Details
Published in:Journal of cardiothoracic and vascular anesthesia 2011-12, Vol.25 (6), p.1000-1004
Main Authors: Dzukou, Thierry, MD, Rakza, Thameur, MD, Bouissou, Antoine, MD, Alexandre, Ceneric, MD, Dalmas, Serge, MD, Storme, Laurent, MD
Format: Article
Language:English
Subjects:
Anesthesia & Perioperative Care
Blood Gas Analysis
Blood Pressure - physiology
Continuous Positive Airway Pressure
Critical Care
ductus arteriosus
Ductus Arteriosus - surgery
Echocardiography, Doppler, Color
Female
Heart Rate - physiology
Humans
Infant
Infant, Newborn
Infant, Premature
Ligation
Lung - physiology
lung function
Male
mechanical ventilation
Oxygen - blood
preterm infants
Respiration, Artificial - adverse effects
Respiration, Artificial - methods
Respiratory Function Tests
Vena Cava, Superior - physiology
Ventricular Function, Left - physiology
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Summary:Objective Significant patent ductus arteriosus (PDA) in the preterm infant has been associated with pulmonary edema and impaired gas exchange. Therefore, surgical ligature of the DA may be required. However, the effects of intubation and mechanical ventilation on the PDA-induced lung dysfunction presently are unknown. The aim of the study was to investigate whether intubation and mechanical ventilation alter pulmonary function in the preterm infant with significant PDA. Design A prospective study. Setting The neonatal intensive care unit and department of anesthesiology in a university hospital. Participants Preterm infants
ISSN:1053-0770
1532-8422
DOI:10.1053/j.jvca.2011.01.010