Right temporal-lobe contribution to the retrieval of family relationships in person identification

• Published in: Neuroscience letters 2010-12, Vol.486 (1), p.10-13
• Main Authors: Abe, Nobuhito, Fujii, Toshikatsu, Ueno, Aya, Shigemune, Yayoi, Suzuki, Maki, Tashiro, Manabu, Mori, Etsuro
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Brain Mapping - methods; Family Relations; Family relationships; Fundamental and applied biological sciences. Psychology; Humans; Male; Person identification; Positron emission tomography (PET); Positron-Emission Tomography - methods; Psychomotor Performance - physiology; Recognition (Psychology) - physiology; Semantic memory; Temporal lobe; Temporal Lobe - diagnostic imaging; Temporal Lobe - physiology; Vertebrates: nervous system and sense organs; Young Adult
• ISSN: 0304-3940; 1872-7972
• DOI: 10.1016/j.neulet.2010.09.031

▶ We found that the right inferior temporal gyrus was significantly activated during the retrieval of family relationships compared with names and occupations. ▶ The present findings, together with our previous case report, support the view that the retrieval of the relationships between oneself and family members may require a special cognitive process dissociated from the retrieval of names and other person-specific semantic information. We previously reported a patient who exhibited a peculiar form of delusional misidentification. She had a selective deficit in retrieving family relationships between herself and her daughters and husband (i.e., she misidentified her daughters as her sisters and her husband as her father) despite being able to retrieve their names and faces and some person-specific semantic information (e.g., occupation). Based on this finding, the present positron emission tomography study was designed to elucidate the brain mechanisms underlying the retrieval of family relationships in healthy individuals. We found that the right inferior temporal gyrus, in which hypoperfusion was detected in the patient we had reported, was significantly activated during the retrieval of family relationships compared with names and occupations. These findings indicate that the retrieval of the relationships between oneself and one's family members may require a specific cognitive process dissociated from the retrieval of names and other person-specific semantic information.