Reporting of meticillin-resistant and -susceptible Staphylococcus aureus on death certificates in Irish hospitals

• Published in: The Journal of hospital infection 2011-02, Vol.77 (2), p.143-147
• Main Authors: Collins, C.J, Fraher, M.H, O’Connell, K, Fennell, J, FitzGerald, S.F, O’Sullivan, N, Cormican, M, Fenelon, L.E, Murphy, P, Hannan, M.M
• Format: Article
• Language: English
• Subjects: Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial diseases; Bacterial sepsis; Biological and medical sciences; Bloodstream infection; Death Certificates; Disease Notification; Documentation - standards; Hospital Mortality; Hospitals - statistics & numerical data; Human bacterial diseases; Humans; Infectious Disease; Infectious diseases; Ireland - epidemiology; Medical sciences; Methicillin-Resistant Staphylococcus aureus - drug effects; Methicillin-Resistant Staphylococcus aureus - isolation & purification; Meticillin-resistant Staphylococcus aureus; Meticillin-susceptible Staphylococcus aureus; Pharmacology. Drug treatments; Reproducibility of Results; Retrospective Studies; Staphylococcal Infections - diagnosis; Staphylococcal Infections - mortality; Staphylococcal infections, streptococcal infections, pneumococcal infections; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - isolation & purification
• ISSN: 0195-6701; 1532-2939
• DOI: 10.1016/j.jhin.2010.10.005

Summary The documentation of infection with meticillin-resistant Staphylococcus aureus (MRSA) on death certificates has been the subject of considerable public discussion. Using data from five tertiary referral hospitals in Ireland, we compared the documentation of MRSA and meticillin-susceptible S. aureus (MSSA) on death certificates in those patients who died in hospital within 30 days of having MRSA or MSSA isolated from blood cultures. A total of 133 patients had MRSA or MSSA isolated from blood cultures within 30 days of death during the study period. One patient was excluded as the death certificate information was not available; the other 132 patients were eligible for inclusion. MRSA and MSSA were isolated from blood cultures in 59 (44.4%) and 74 (55.6%) cases respectively. One patient was included as a case in both categories as both MRSA and MSSA were isolated from a blood culture. In 15 (25.4%) of the 59 MRSA cases, MRSA was documented on the death certificate. In nine (12.2%) of the 74 patients with MSSA cases, MSSA was documented on the death certificate. MRSA was more likely to be documented on the death certificate than MSSA (odds ratio: 2.46; 95% confidence interval: 1.01–6.01; P < 0.05). These findings indicate that there may be inconsistencies in the way organisms and infections are documented on death certificates in Ireland and that death certification data may underestimate the mortality related to certain organisms. In particular, there appears to be an overemphasis by certifiers on the documentation of MRSA compared with MSSA.