Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression

Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost identical, but 5% of their genes were uniquely expressed. These results help us to choose an optimal cell source for effective fibroblast-ba...

Full description

Saved in:
Bibliographic Details
Published in:Journal of bioscience and bioengineering 2011-03, Vol.111 (3), p.255-258
Main Authors: Ebisawa, Katsumi, Kato, Ryuji, Okada, Mai, Sugimura, Tomotaka, Latif, Mazlyzam Abdul, Hori, Yusuke, Narita, Yuji, Ueda, Minoru, Honda, Hiroyuki, Kagami, Hideaki
Format: Article
Language:English
Subjects:
Adult
Anti-aging
Antioxidant
Biological and medical sciences
Biotechnology
Cells, Cultured
Female
Fibroblast
Fibroblasts - metabolism
Fundamental and applied biological sciences. Psychology
Gene Expression Profiling
Gingiva - cytology
Gingival tissue
Humans
Insulin-Like Growth Factor II - metabolism
Male
Microarray
Middle Aged
Oligonucleotide Array Sequence Analysis
Skin - cytology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost identical, but 5% of their genes were uniquely expressed. These results help us to choose an optimal cell source for effective fibroblast-based cell therapy that is dependent on differential gene expression profiles.
ISSN:1389-1723
1347-4421
DOI:10.1016/j.jbiosc.2010.11.014