Brucellosis in pregnancy

This study was undertaken in order to evaluate the effect of brucellosis in pregnancy. The serum agglutination test, Coombs and/or blood culture systems were used in the diagnosis of brucellosis. From July 2003 to September 2010, the clinical and delivery patterns of 40 healthy pregnant women were c...

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Bibliographic Details
Published in:Tropical doctor 2011-04, Vol.41 (2), p.82-84
Main Authors: Gulsun, Serda, Aslan, Selda, Satici, Omer, Gul, Talip
Format: Article
Language:English
Subjects:
Adult
Agglutination Tests
Anti-Infective Agents - therapeutic use
Antibodies, Bacterial - blood
Bacterial diseases
Biological and medical sciences
Brucella melitensis - isolation & purification
Brucellosis - complications
Brucellosis - diagnosis
Brucellosis - drug therapy
Case-Control Studies
Coombs Test
Drug Therapy, Combination
Female
Follow-Up Studies
General aspects
Human bacterial diseases
Humans
Incidence
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infectious diseases
Medical sciences
Miscellaneous
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - drug therapy
Pregnancy Complications, Infectious - microbiology
Pregnancy Outcome
Premature Birth
Rifampin - therapeutic use
Turkey - epidemiology
Young Adult
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Summary:This study was undertaken in order to evaluate the effect of brucellosis in pregnancy. The serum agglutination test, Coombs and/or blood culture systems were used in the diagnosis of brucellosis. From July 2003 to September 2010, the clinical and delivery patterns of 40 healthy pregnant women were compared with 39 pregnant women who had brucellosis. There were no birth defects, anomalies or mortalities. We observed that brucellosis in pregnancy increases the incidence of preterm delivery (P = 0.01) and low birth weight (P = 0.001) from that seen in general deliveries. A cephtriaxone/rifampicin combination was found to be the most effective treatment in pregnant women infected with brucellosis (P = 0.004). Brucellosis in pregnancy has no effect on the incidence of congenital malformations or stillbirths. Preterm delivery and low birth weight can be seen as pregnancy outcomes in brucellosis. Appropriate antimicrobial therapy of brucellosis in pregnancy will reduce morbidity and prevent complications.
ISSN:0049-4755
1758-1133
DOI:10.1258/td.2011.100386