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Mycotoxins in broilers: pathological alterations induced by aflatoxins and ochratoxins, diagnosis and determination, treatment and control of mycotoxicosis

Mycotoxins are secondary metabolites produced by fungi. Mycotoxins in feed are considered the second most serious issue in the poultry industry, following increased feed prices. There are different types of mycotoxins, including aflatoxins, ochratoxins, fumonisin, trichothecenes, zearalenone, patuli...

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Published in:World's poultry science journal 2011-09, Vol.67 (3), p.485-496
Main Authors: ABIDIN, Z., KHATOON, A., NUMAN, M.
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description Mycotoxins are secondary metabolites produced by fungi. Mycotoxins in feed are considered the second most serious issue in the poultry industry, following increased feed prices. There are different types of mycotoxins, including aflatoxins, ochratoxins, fumonisin, trichothecenes, zearalenone, patulin, but the most important are aflatoxins and ochratoxins. Ochratoxin is known as a nephrotoxin as it damages kidney tissues predominantly, whereas aflatoxin has more adverse effects upon the liver. Diagnosis and determination of toxins can be done in tissues and feed samples by using different techniques such as high performance liquid chromatography (HPLC), thin layer liquid chromatography (TLC), and fluorescence polarization immunoassay (FPIA). Treatment of mycotoxicosis can be done by decontamination or detoxification of feed by using mycotoxin binders, plant preparations (nutraceuticals) and vitamins. Mycotoxicosis can be controlled by using transgenic crops and improving harvesting management, storing feed in good environmental conditions and fresh feed for the birds. Hazard analysis critical control point (HACCP) should be referred to for the control of mycotoxins in the food chain.
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subjects adverse effects
aflatoxin
Aflatoxins
Binders
birds
Decontamination
Detoxification
Environmental conditions
environmental factors
feed prices
Feeds
fluorescence
food chain
functional foods
Functional foods & nutraceuticals
fungi
HACCP
high performance liquid chromatography
immunoassays
kidneys
Liquid chromatography
liver
Metabolites
mycotoxicosis
Mycotoxins
ochratoxin
ochratoxins
pathological alterations
patulin
Plant preparations
poultry industry
Secondary metabolites
Toxins
Transgenic plants
trichothecenes
Vitamins
zearalenone
title Mycotoxins in broilers: pathological alterations induced by aflatoxins and ochratoxins, diagnosis and determination, treatment and control of mycotoxicosis
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