Structure of the oligosaccharide region (core) of the lipopolysaccharides of Shigella flexneri types 2a and 5b

The full structure of the lipopolysaccharide core of bacteria Shigella flexneri types 2a and 5b, the causative agents of bacillary dysentery (shigellosis), was established by chemical methods, high-resolution electrospray ionization mass spectrometry, and two-dimensional NMR spectroscopy. The struct...

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Bibliographic Details
Published in:Russian journal of bioorganic chemistry 2010-05, Vol.36 (3), p.396-399
Main Authors: Kondakova, A. N, Vinogradov, E. V, Shekht, M. E, Markina, A. A, Lindner, B, L'vov, V. L, Aparin, P. G, Knirel, Yu. A
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Letter to the Editor
Life Sciences
lipopolysaccharide
O-antigen
oligosaccharide
Organic Chemistry
Shigella flexneri
structure
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Summary:The full structure of the lipopolysaccharide core of bacteria Shigella flexneri types 2a and 5b, the causative agents of bacillary dysentery (shigellosis), was established by chemical methods, high-resolution electrospray ionization mass spectrometry, and two-dimensional NMR spectroscopy. The structure of the O-antigen repeating unit and the configuration and position of the linkage between the O-antigen and the core were determined in the lipopolysaccharide of S. flexneri type 2a.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162010030179