Stepwise and reversible nanopatterning of proteins on a DNA origami scaffold

Stepwise introduction of multiple streptavidin tetramers into a nanoarray formed in a stick-like punched DNA origami as well as selective removal of predetermined tetramer from the array were successfully achieved by applying a programmed strand displacement technique to a DNA origami scaffold.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (28), p.5127-5129
Main Authors: Numajiri, Kentaro, Kimura, Mayumi, Kuzuya, Akinori, Komiyama, Makoto
Format: Article
Language:English
Subjects:
Biotin - chemistry
DNA - chemistry
Microscopy, Atomic Force
Nanostructures - chemistry
Nucleic Acid Hybridization
Streptavidin - chemistry
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Description
Summary:Stepwise introduction of multiple streptavidin tetramers into a nanoarray formed in a stick-like punched DNA origami as well as selective removal of predetermined tetramer from the array were successfully achieved by applying a programmed strand displacement technique to a DNA origami scaffold.
ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc00044b