Small molecule-triggered assembly of DNA nanoarchitectures

The utilization of toehold-containing DNA strands allows for the assembly of complex nanostructures via kinetically driven hybridization reactions. Here, we have rendered this strategy ligand-dependent, resulting in small-molecule-inducible DNA nanoarchitectures.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (11), p.1866-1868
Main Authors: Wieland, Markus, Benz, Armin, Haar, Janina, Halder, Kangkan, Hartig, Jörg S
Format: Article
Language:English
Subjects:
Aptamers, Nucleotide - chemistry
Arginine - chemistry
DNA - chemistry
Nanostructures - chemistry
Nucleic Acid Conformation
Nucleic Acid Hybridization
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Description
Summary:The utilization of toehold-containing DNA strands allows for the assembly of complex nanostructures via kinetically driven hybridization reactions. Here, we have rendered this strategy ligand-dependent, resulting in small-molecule-inducible DNA nanoarchitectures.
ISSN:1359-7345
1364-548X
DOI:10.1039/b921481j