Fe3O4 nanoparticles: a robust and magnetically recoverable catalyst for three-component coupling of aldehyde, alkyne and amine

A robust, safe and magnetically recoverable Fe3O4 nanoparticle catalyzed three-component coupling of aldehyde, alkyne, and amine (A3-coupling) was developed. A diverse range of propargylamines were obtained in moderate to high yield under mild conditions in air. The separation and reuse of the magne...

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Bibliographic Details
Published in:Green chemistry : an international journal and green chemistry resource : GC 2010-01, Vol.12 (4), p.570-573
Main Authors: Zeng, Tieqiang, Chen, Wen-Wen, Cirtiu, Ciprian M, Moores, Audrey, Song, Gonghua, Li, Chao-Jun
Format: Article
Language:English
Subjects:
Aldehydes
Alkynes
Amines
Economics
Joining
Nanoparticles
Reuse
Separation
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Summary:A robust, safe and magnetically recoverable Fe3O4 nanoparticle catalyzed three-component coupling of aldehyde, alkyne, and amine (A3-coupling) was developed. A diverse range of propargylamines were obtained in moderate to high yield under mild conditions in air. The separation and reuse of the magnetic Fe3O4 nanoparticles were very simple, effective and economical.
ISSN:1463-9262
1463-9270
DOI:10.1039/B920000B