Frequency analysis of high-intensity transient signals of transcranial Doppler ultrasound in patients supported with a left ventricular assist device

Left ventricular assist devices (LVADs) have become more important than ever for patients with terminal heart disease. The chronic shortage of donors for heart transplantation may enhance the importance of LVADs as destination therapy. To prevent cerebral complications, the evaluation of high-intens...

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Bibliographic Details
Published in:Journal of artificial organs 2008-12, Vol.11 (4), p.201-203
Main Authors: Sato, Koichi, Hanzawa, Kazuhiko, Okamoto, Takeshi, Kyo, Shunei, Hayashi, Jun-ichi
Format: Article
Language:English
Subjects:
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cerebrovascular Disorders - diagnosis
Cerebrovascular Disorders - etiology
Heart-Assist Devices - adverse effects
Humans
Medical research
Medicine
Medicine & Public Health
Nephrology
Original Article
Ultrasonic imaging
Ultrasonography, Doppler, Transcranial
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Summary:Left ventricular assist devices (LVADs) have become more important than ever for patients with terminal heart disease. The chronic shortage of donors for heart transplantation may enhance the importance of LVADs as destination therapy. To prevent cerebral complications, the evaluation of high-intensity transient signals (HITS) of transcranial Doppler (TCD) ultrasound is important. In the present study, HITS were measured on seven occasions in patients supported with LVADs. The high-frequency counts in HITS were greater than the low-frequency counts (47 ± 42 vs. 9 ± 9 in 3 min, P = 0.025), and declined further with oxygen delivery to the patient. The high frequency of signals may imply air microemboli, and the counts may increase with time.
ISSN:1434-7229
1619-0904
DOI:10.1007/s10047-008-0430-7