Regression of HIV-associated grade IV T cell lymphoma with combined antiretroviral therapy only

The present report describes repeated long-term remissions of a high-grade T cell lymphoma in an HIV-positive patient upon cART only, without additional chemotherapy. A review of cases from the literature further illustrates the anti-tumor effects of cART through the induction of a strong immune rec...

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Bibliographic Details
Published in:International journal of hematology 2011-06, Vol.93 (6), p.811-814
Main Authors: Teng, Y. K. O., Schippers, E. F., Wijermans, P. W.
Format: Article
Language:English
Subjects:
Anti-HIV Agents - therapeutic use
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Bone and Bones - pathology
Case Report
CD4 Lymphocyte Count
Hematologic and hematopoietic diseases
Hematology
HIV Infections - complications
Human immunodeficiency virus
Human viral diseases
Humans
Infectious diseases
Lymphoma, AIDS-Related - diagnosis
Lymphoma, AIDS-Related - drug therapy
Lymphoma, AIDS-Related - pathology
Lymphoma, T-Cell - diagnosis
Lymphoma, T-Cell - drug therapy
Lymphoma, T-Cell - pathology
Male
Medical sciences
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Staging
Oncology
Positron-Emission Tomography
Tomography, X-Ray Computed
Treatment Outcome
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral Load
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Description
Summary:The present report describes repeated long-term remissions of a high-grade T cell lymphoma in an HIV-positive patient upon cART only, without additional chemotherapy. A review of cases from the literature further illustrates the anti-tumor effects of cART through the induction of a strong immune reconstitution in HIV-infected patients.
ISSN:0925-5710
1865-3774
DOI:10.1007/s12185-011-0859-y