Cortical Circuits: Finding Balance in the Brain

Maintaining the right balance between excitation and inhibition is crucial to healthy brain function. A recent study has used optogenetics to show how quickly and effectively inhibition clamps down a novel burst of excitation in the neocortex.

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Bibliographic Details
Published in:Current biology 2011-12, Vol.21 (23), p.R956-R957
Main Authors: Siegle, Joshua H., Moore, Christopher I.
Format: Article
Language:English
Subjects:
Brain
Circuits
Cortex
Excitatory Postsynaptic Potentials - physiology
Genetics
Humans
Information processing
Interneurons - physiology
mental health
Models, Neurological
neocortex
Neocortex - physiology
Neural Inhibition - physiology
Neural Pathways - physiology
Optics
optogenetics
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Description
Summary:Maintaining the right balance between excitation and inhibition is crucial to healthy brain function. A recent study has used optogenetics to show how quickly and effectively inhibition clamps down a novel burst of excitation in the neocortex.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2011.10.026