Development and applications of a microfluidic reactor with multiple analytical probes

We report the development of a versatile microfluidic (MF) reactor with multiple analytical probes, which can be used for (i) quantitative characterisation of molecular vibrational signatures of reactants or products, (ii) the localised real-time monitoring of temperature and (iii) site-specific mea...

Full description

Saved in:
Bibliographic Details
Published in:Analyst (London) 2012-01, Vol.137 (2), p.444-450
Main Authors: GREENER, Jesse, TUMARKIN, Ethan, DEBONO, Michael, KWAN, Chi-Hang, ABOLHASANI, Milad, GUENTHER, Axel, KUMACHEVA, Eugenia
Format: Article
Language:English
Subjects:
Analytical chemistry
Buffers
Carbon dioxide
Carbon Dioxide - chemistry
Chemistry
Exact sciences and technology
Hydrogen-Ion Concentration
Kinetics
Mathematical analysis
Microfluidic Analytical Techniques
Microfluidics
Microscopy, Atomic Force
Molecular Probes
Monitoring
Reactors
Spectrometric and optical methods
Spectroscopy, Fourier Transform Infrared
Temperature
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report the development of a versatile microfluidic (MF) reactor with multiple analytical probes, which can be used for (i) quantitative characterisation of molecular vibrational signatures of reactants or products, (ii) the localised real-time monitoring of temperature and (iii) site-specific measurements of pH of the reaction system. The analytical probes utilised for in situ reaction analysis include an ATR-FTIR probe, a temperature probe, and a pH probe. We demonstrate the applications of the MF reactor with integrated probes for the parallel monitoring of multiple variables in acid/base neutralisation reaction, of changes in buffer pH, temperature, and vibrational absorption bands, and for monitoring the kinetics of the reaction between CO(2) and a buffer system with therapeutic applications.
ISSN:0003-2654
1364-5528
DOI:10.1039/c1an15940b