Loading…
Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies
Since selenium supplements have been shown to undergo biotransformation in the gut, probiotic treatment in combination with selenium supplements may change selenium disposition. We investigated the metabolism of L-selenomethionine (SeMet) and selenite by probiotic bacteria in vitro and the dispositi...
Saved in:
Published in: | Biological trace element research 2011-12, Vol.144 (1-3), p.1358-1369 |
---|---|
Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793 |
---|---|
cites | cdi_FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793 |
container_end_page | 1369 |
container_issue | 1-3 |
container_start_page | 1358 |
container_title | Biological trace element research |
container_volume | 144 |
creator | Krittaphol, Woravimol Wescombe, Philip A Thomson, Christine D McDowell, Arlene Tagg, John R Fawcett, J. Paul |
description | Since selenium supplements have been shown to undergo biotransformation in the gut, probiotic treatment in combination with selenium supplements may change selenium disposition. We investigated the metabolism of L-selenomethionine (SeMet) and selenite by probiotic bacteria in vitro and the disposition of selenium after probiotic treatment followed by oral dosing with SeMet and selenite in rats. When SeMet was incubated anaerobically with individual antibiotic-resistant probiotic strains (Streptococcus salivarius K12, Lactobacillus rhamnosus 67B, Lactobacillus acidophilus L10, and Bifidobacterium lactis LAFTI® B94) at 37°C for 24 h, 11–18% was metabolized with 44-80% of SeMet lost being converted to dimethyldiselenide (DMDSe) and dimethylselenide (DMSe). In similar incubations with selenite, metabolism was more extensive (26–100%) particularly by the lactobacilli with 0-4.8% of selenite lost being converted to DMSe and DMDSe accompanied by the formation of elemental selenium. Four groups of rats (n = 5/group) received a single oral dose of either SeMet or selenite (2 mg selenium/kg) at the time of the last dose of a probiotic mixture or its vehicle (lyoprotectant mixture used to maintain cell viability) administered every 12 h for 3 days. Another three groups of rats (n = 3/group) received a single oral dose of saline or SeMet or selenite at the same dose (untreated rats). Serum selenium concentrations over the subsequent 24 h were not significantly different between probiotic and vehicle treated rats but appeared to be more sustained (SeMet) or higher (selenite) than in the corresponding groups of untreated rats. Probiotic treated rats given SeMet also had selenium concentrations at 24 h that were significantly higher in liver and lower in kidney than untreated rats given SeMet. Thus, treatment with probiotics followed by SeMet significantly affects tissue levels of selenium. |
doi_str_mv | 10.1007/s12011-011-9057-2 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_912106519</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1014107933</sourcerecordid><originalsourceid>FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793</originalsourceid><addsrcrecordid>eNp9kU1P3DAQhi1EVba0P6CXYvVCL2k9_ohjbhT1A2kRlbZwteysQ42SGGwHiX9fZ0NbqQcOI8v2M89o9CL0FshHIER-SkAJQDWXIkJWdA-tQAhVEUnJPloRqFnFVcMP0KuUbgkBSRV7iQ4ocMUbwlbIXLhsbOh9GnDo8LrauN6NYXD5lw-jHx024xbvHn122D7iHzFYH7Jv8WfTZhe9OcHnI772OYYdvLs8BLzJ09a79Bq96Eyf3Jun8xBdff3y8-x7tb78dn52uq5aTmWubN06JVxTAzWU2s5Y2VmruFAKpDEda0DWbGtaqCUH4MQKIUjZn0hmlVTsEB0v3rsY7ieXsh58al3fm9GFKWkFFEgtYCY_PEsCAV60irGCvv8PvQ1THMsexQe8UaB4gWCB2hhSiq7Td9EPJj4Wk56D0ktQeq45KE1Lz7sn8WQHt_3b8SeZAtAFSOVrvHHx3-TnrEdLU2eCNjfRJ321KRCfo69V0f4GG6ykGg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>911489194</pqid></control><display><type>article</type><title>Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies</title><source>Springer Link</source><creator>Krittaphol, Woravimol ; Wescombe, Philip A ; Thomson, Christine D ; McDowell, Arlene ; Tagg, John R ; Fawcett, J. Paul</creator><creatorcontrib>Krittaphol, Woravimol ; Wescombe, Philip A ; Thomson, Christine D ; McDowell, Arlene ; Tagg, John R ; Fawcett, J. Paul</creatorcontrib><description>Since selenium supplements have been shown to undergo biotransformation in the gut, probiotic treatment in combination with selenium supplements may change selenium disposition. We investigated the metabolism of L-selenomethionine (SeMet) and selenite by probiotic bacteria in vitro and the disposition of selenium after probiotic treatment followed by oral dosing with SeMet and selenite in rats. When SeMet was incubated anaerobically with individual antibiotic-resistant probiotic strains (Streptococcus salivarius K12, Lactobacillus rhamnosus 67B, Lactobacillus acidophilus L10, and Bifidobacterium lactis LAFTI® B94) at 37°C for 24 h, 11–18% was metabolized with 44-80% of SeMet lost being converted to dimethyldiselenide (DMDSe) and dimethylselenide (DMSe). In similar incubations with selenite, metabolism was more extensive (26–100%) particularly by the lactobacilli with 0-4.8% of selenite lost being converted to DMSe and DMDSe accompanied by the formation of elemental selenium. Four groups of rats (n = 5/group) received a single oral dose of either SeMet or selenite (2 mg selenium/kg) at the time of the last dose of a probiotic mixture or its vehicle (lyoprotectant mixture used to maintain cell viability) administered every 12 h for 3 days. Another three groups of rats (n = 3/group) received a single oral dose of saline or SeMet or selenite at the same dose (untreated rats). Serum selenium concentrations over the subsequent 24 h were not significantly different between probiotic and vehicle treated rats but appeared to be more sustained (SeMet) or higher (selenite) than in the corresponding groups of untreated rats. Probiotic treated rats given SeMet also had selenium concentrations at 24 h that were significantly higher in liver and lower in kidney than untreated rats given SeMet. Thus, treatment with probiotics followed by SeMet significantly affects tissue levels of selenium.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-011-9057-2</identifier><identifier>PMID: 21494803</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Animals ; Antibiotic resistance ; Bacteria ; Bacteria - metabolism ; Bacterial Load ; Bifidobacterium animalis ; Bifidobacterium lactis ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Biotransformation ; blood serum ; cell viability ; Chemistry, Pharmaceutical ; Excipients ; Gastrointestinal Tract - metabolism ; Gastrointestinal Tract - microbiology ; Kidney - metabolism ; kidneys ; Lactobacillus acidophilus ; Lactobacillus rhamnosus ; Life Sciences ; Linear Models ; liver ; Liver - metabolism ; Male ; Metabolism ; Nutrition ; Oncology ; Organoselenium Compounds - metabolism ; Probiotics ; Probiotics - metabolism ; Rats ; Rats, Wistar ; Rodents ; Selenium ; selenomethionine ; Selenomethionine - metabolism ; Sodium Selenite - metabolism ; Streptococcus salivarius</subject><ispartof>Biological trace element research, 2011-12, Vol.144 (1-3), p.1358-1369</ispartof><rights>Springer Science+Business Media, LLC 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793</citedby><cites>FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21494803$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krittaphol, Woravimol</creatorcontrib><creatorcontrib>Wescombe, Philip A</creatorcontrib><creatorcontrib>Thomson, Christine D</creatorcontrib><creatorcontrib>McDowell, Arlene</creatorcontrib><creatorcontrib>Tagg, John R</creatorcontrib><creatorcontrib>Fawcett, J. Paul</creatorcontrib><title>Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>Since selenium supplements have been shown to undergo biotransformation in the gut, probiotic treatment in combination with selenium supplements may change selenium disposition. We investigated the metabolism of L-selenomethionine (SeMet) and selenite by probiotic bacteria in vitro and the disposition of selenium after probiotic treatment followed by oral dosing with SeMet and selenite in rats. When SeMet was incubated anaerobically with individual antibiotic-resistant probiotic strains (Streptococcus salivarius K12, Lactobacillus rhamnosus 67B, Lactobacillus acidophilus L10, and Bifidobacterium lactis LAFTI® B94) at 37°C for 24 h, 11–18% was metabolized with 44-80% of SeMet lost being converted to dimethyldiselenide (DMDSe) and dimethylselenide (DMSe). In similar incubations with selenite, metabolism was more extensive (26–100%) particularly by the lactobacilli with 0-4.8% of selenite lost being converted to DMSe and DMDSe accompanied by the formation of elemental selenium. Four groups of rats (n = 5/group) received a single oral dose of either SeMet or selenite (2 mg selenium/kg) at the time of the last dose of a probiotic mixture or its vehicle (lyoprotectant mixture used to maintain cell viability) administered every 12 h for 3 days. Another three groups of rats (n = 3/group) received a single oral dose of saline or SeMet or selenite at the same dose (untreated rats). Serum selenium concentrations over the subsequent 24 h were not significantly different between probiotic and vehicle treated rats but appeared to be more sustained (SeMet) or higher (selenite) than in the corresponding groups of untreated rats. Probiotic treated rats given SeMet also had selenium concentrations at 24 h that were significantly higher in liver and lower in kidney than untreated rats given SeMet. Thus, treatment with probiotics followed by SeMet significantly affects tissue levels of selenium.</description><subject>Animals</subject><subject>Antibiotic resistance</subject><subject>Bacteria</subject><subject>Bacteria - metabolism</subject><subject>Bacterial Load</subject><subject>Bifidobacterium animalis</subject><subject>Bifidobacterium lactis</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Biotransformation</subject><subject>blood serum</subject><subject>cell viability</subject><subject>Chemistry, Pharmaceutical</subject><subject>Excipients</subject><subject>Gastrointestinal Tract - metabolism</subject><subject>Gastrointestinal Tract - microbiology</subject><subject>Kidney - metabolism</subject><subject>kidneys</subject><subject>Lactobacillus acidophilus</subject><subject>Lactobacillus rhamnosus</subject><subject>Life Sciences</subject><subject>Linear Models</subject><subject>liver</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Metabolism</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Organoselenium Compounds - metabolism</subject><subject>Probiotics</subject><subject>Probiotics - metabolism</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Rodents</subject><subject>Selenium</subject><subject>selenomethionine</subject><subject>Selenomethionine - metabolism</subject><subject>Sodium Selenite - metabolism</subject><subject>Streptococcus salivarius</subject><issn>0163-4984</issn><issn>1559-0720</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kU1P3DAQhi1EVba0P6CXYvVCL2k9_ohjbhT1A2kRlbZwteysQ42SGGwHiX9fZ0NbqQcOI8v2M89o9CL0FshHIER-SkAJQDWXIkJWdA-tQAhVEUnJPloRqFnFVcMP0KuUbgkBSRV7iQ4ocMUbwlbIXLhsbOh9GnDo8LrauN6NYXD5lw-jHx024xbvHn122D7iHzFYH7Jv8WfTZhe9OcHnI772OYYdvLs8BLzJ09a79Bq96Eyf3Jun8xBdff3y8-x7tb78dn52uq5aTmWubN06JVxTAzWU2s5Y2VmruFAKpDEda0DWbGtaqCUH4MQKIUjZn0hmlVTsEB0v3rsY7ieXsh58al3fm9GFKWkFFEgtYCY_PEsCAV60irGCvv8PvQ1THMsexQe8UaB4gWCB2hhSiq7Td9EPJj4Wk56D0ktQeq45KE1Lz7sn8WQHt_3b8SeZAtAFSOVrvHHx3-TnrEdLU2eCNjfRJ321KRCfo69V0f4GG6ykGg</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Krittaphol, Woravimol</creator><creator>Wescombe, Philip A</creator><creator>Thomson, Christine D</creator><creator>McDowell, Arlene</creator><creator>Tagg, John R</creator><creator>Fawcett, J. Paul</creator><general>Springer-Verlag</general><general>Humana Press Inc</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7QP</scope><scope>7TN</scope><scope>7U7</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies</title><author>Krittaphol, Woravimol ; Wescombe, Philip A ; Thomson, Christine D ; McDowell, Arlene ; Tagg, John R ; Fawcett, J. Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Antibiotic resistance</topic><topic>Bacteria</topic><topic>Bacteria - metabolism</topic><topic>Bacterial Load</topic><topic>Bifidobacterium animalis</topic><topic>Bifidobacterium lactis</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Biotransformation</topic><topic>blood serum</topic><topic>cell viability</topic><topic>Chemistry, Pharmaceutical</topic><topic>Excipients</topic><topic>Gastrointestinal Tract - metabolism</topic><topic>Gastrointestinal Tract - microbiology</topic><topic>Kidney - metabolism</topic><topic>kidneys</topic><topic>Lactobacillus acidophilus</topic><topic>Lactobacillus rhamnosus</topic><topic>Life Sciences</topic><topic>Linear Models</topic><topic>liver</topic><topic>Liver - metabolism</topic><topic>Male</topic><topic>Metabolism</topic><topic>Nutrition</topic><topic>Oncology</topic><topic>Organoselenium Compounds - metabolism</topic><topic>Probiotics</topic><topic>Probiotics - metabolism</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Rodents</topic><topic>Selenium</topic><topic>selenomethionine</topic><topic>Selenomethionine - metabolism</topic><topic>Sodium Selenite - metabolism</topic><topic>Streptococcus salivarius</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krittaphol, Woravimol</creatorcontrib><creatorcontrib>Wescombe, Philip A</creatorcontrib><creatorcontrib>Thomson, Christine D</creatorcontrib><creatorcontrib>McDowell, Arlene</creatorcontrib><creatorcontrib>Tagg, John R</creatorcontrib><creatorcontrib>Fawcett, J. Paul</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aqualine</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krittaphol, Woravimol</au><au>Wescombe, Philip A</au><au>Thomson, Christine D</au><au>McDowell, Arlene</au><au>Tagg, John R</au><au>Fawcett, J. Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies</atitle><jtitle>Biological trace element research</jtitle><stitle>Biol Trace Elem Res</stitle><addtitle>Biol Trace Elem Res</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>144</volume><issue>1-3</issue><spage>1358</spage><epage>1369</epage><pages>1358-1369</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>Since selenium supplements have been shown to undergo biotransformation in the gut, probiotic treatment in combination with selenium supplements may change selenium disposition. We investigated the metabolism of L-selenomethionine (SeMet) and selenite by probiotic bacteria in vitro and the disposition of selenium after probiotic treatment followed by oral dosing with SeMet and selenite in rats. When SeMet was incubated anaerobically with individual antibiotic-resistant probiotic strains (Streptococcus salivarius K12, Lactobacillus rhamnosus 67B, Lactobacillus acidophilus L10, and Bifidobacterium lactis LAFTI® B94) at 37°C for 24 h, 11–18% was metabolized with 44-80% of SeMet lost being converted to dimethyldiselenide (DMDSe) and dimethylselenide (DMSe). In similar incubations with selenite, metabolism was more extensive (26–100%) particularly by the lactobacilli with 0-4.8% of selenite lost being converted to DMSe and DMDSe accompanied by the formation of elemental selenium. Four groups of rats (n = 5/group) received a single oral dose of either SeMet or selenite (2 mg selenium/kg) at the time of the last dose of a probiotic mixture or its vehicle (lyoprotectant mixture used to maintain cell viability) administered every 12 h for 3 days. Another three groups of rats (n = 3/group) received a single oral dose of saline or SeMet or selenite at the same dose (untreated rats). Serum selenium concentrations over the subsequent 24 h were not significantly different between probiotic and vehicle treated rats but appeared to be more sustained (SeMet) or higher (selenite) than in the corresponding groups of untreated rats. Probiotic treated rats given SeMet also had selenium concentrations at 24 h that were significantly higher in liver and lower in kidney than untreated rats given SeMet. Thus, treatment with probiotics followed by SeMet significantly affects tissue levels of selenium.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>21494803</pmid><doi>10.1007/s12011-011-9057-2</doi><tpages>12</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0163-4984 |
ispartof | Biological trace element research, 2011-12, Vol.144 (1-3), p.1358-1369 |
issn | 0163-4984 1559-0720 |
language | eng |
recordid | cdi_proquest_miscellaneous_912106519 |
source | Springer Link |
subjects | Animals Antibiotic resistance Bacteria Bacteria - metabolism Bacterial Load Bifidobacterium animalis Bifidobacterium lactis Biochemistry Biomedical and Life Sciences Biotechnology Biotransformation blood serum cell viability Chemistry, Pharmaceutical Excipients Gastrointestinal Tract - metabolism Gastrointestinal Tract - microbiology Kidney - metabolism kidneys Lactobacillus acidophilus Lactobacillus rhamnosus Life Sciences Linear Models liver Liver - metabolism Male Metabolism Nutrition Oncology Organoselenium Compounds - metabolism Probiotics Probiotics - metabolism Rats Rats, Wistar Rodents Selenium selenomethionine Selenomethionine - metabolism Sodium Selenite - metabolism Streptococcus salivarius |
title | Metabolism of L-Selenomethionine and Selenite by Probiotic Bacteria: In Vitro and In Vivo Studies |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T16%3A55%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Metabolism%20of%20L-Selenomethionine%20and%20Selenite%20by%20Probiotic%20Bacteria:%20In%20Vitro%20and%20In%20Vivo%20Studies&rft.jtitle=Biological%20trace%20element%20research&rft.au=Krittaphol,%20Woravimol&rft.date=2011-12-01&rft.volume=144&rft.issue=1-3&rft.spage=1358&rft.epage=1369&rft.pages=1358-1369&rft.issn=0163-4984&rft.eissn=1559-0720&rft_id=info:doi/10.1007/s12011-011-9057-2&rft_dat=%3Cproquest_cross%3E1014107933%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c427t-b6ce95e8612a22bfab7fbb9459917aaf381763dac16741140b5550201073b9793%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=911489194&rft_id=info:pmid/21494803&rfr_iscdi=true |