Migraine and hypercoagulable states in ischemic stroke

Background: Whether migraine is associated with a higher prevalence of hypercoagulable states (HS) in ischemic stroke patients is unknown. Methods: This was a prospective study of patients under 55 years of age with brain ischemia. A systematic questionnaire addressed the antecedent of migraine with...

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Bibliographic Details
Published in:Cephalalgia 2011-12, Vol.31 (16), p.1609-1617
Main Authors: Martínez-Sánchez, P, Martínez-Martínez, M, Fuentes, B, Cuesta, MV, Cuéllar-Gamboa, L, Idrovo-Freire, L, Fernández-Dominguez, J, Díez-Tejedor, E
Format: Article
Language:English
Subjects:
Adult
Brain Ischemia - etiology
Female
Foramen Ovale, Patent
Humans
Male
Middle Aged
Migraine Disorders - complications
Prevalence
Risk Factors
Stroke - etiology
Surveys and Questionnaires
Thrombophilia - complications
Thrombophilia - epidemiology
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Summary:Background: Whether migraine is associated with a higher prevalence of hypercoagulable states (HS) in ischemic stroke patients is unknown. Methods: This was a prospective study of patients under 55 years of age with brain ischemia. A systematic questionnaire addressed the antecedent of migraine with aura (MA) or without aura (MO). We investigated the presence of HS by an extensive battery of haematological tests. The presence of patent foramen ovale (PFO) was assessed by trans-oesophageal echocardiography. Results: A total of 154 patients (95 men; mean ± SD age, 44.12 ± 8.4 years) were included; 44 had migraine, 15 had MA. HS were more frequent in the migraine than non-migraine group (38.6% vs. 16.4%, p 
ISSN:0333-1024
1468-2982
DOI:10.1177/0333102411427599