Osteomeatal complex obstruction is not associated with adjacent sinus disease in chronic rhinosinusitis with polyps

It is universally accepted that osteomeatal complex (OMC) disease is linked to the subsequent development of chronic rhinosinusitis without nasal polyps (CRSsNPs) via postobstructive mechanisms. The role of OMC obstruction in the pathogenesis of CRSwNPs is less clear. This study was designed to iden...

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Bibliographic Details
Published in:American journal of rhinology & allergy 2011-11, Vol.25 (6), p.401-403
Main Authors: Leung, Randy M, Kern, Robert C, Conley, David B, Tan, Bruce K, Chandra, Rakesh K
Format: Article
Language:English
Subjects:
Adult
Chronic Disease
Female
Follow-Up Studies
Humans
Male
Nasal Obstruction - complications
Nasal Obstruction - epidemiology
Nasal Obstruction - pathology
Nasal Obstruction - physiopathology
Nasal Polyps - complications
Nasal Polyps - epidemiology
Nasal Polyps - pathology
Nasal Polyps - physiopathology
Paranasal Sinuses - diagnostic imaging
Paranasal Sinuses - immunology
Paranasal Sinuses - pathology
Pilot Projects
Prospective Studies
Rhinitis - complications
Rhinitis - epidemiology
Rhinitis - pathology
Rhinitis - physiopathology
Sinusitis - complications
Sinusitis - epidemiology
Sinusitis - pathology
Sinusitis - physiopathology
Tomography, X-Ray Computed
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Summary:It is universally accepted that osteomeatal complex (OMC) disease is linked to the subsequent development of chronic rhinosinusitis without nasal polyps (CRSsNPs) via postobstructive mechanisms. The role of OMC obstruction in the pathogenesis of CRSwNPs is less clear. This study was designed to identify if there is an association between OMC obstruction and inflammation of the adjacent sinuses, when patients are stratified by polyp status. This is a follow-up and expanded series of a previous pilot study from our group. CT scans of 144 patients with CRSsNPs and 123 patients with CRS with nasal polyps (CRSwNPs) were evaluated for each sinus and OMC. Patients had no previous surgeries for NPs. CT scans were obtained after a trial of maximal medical therapy. Increasing OMC involvement was associated with increasing Lund-Mackay score for both CRSsNPs and CRSwNPs. In CRSsNP patients, OMC status significantly correlated with adjacent sinus status (p
ISSN:1945-8924
1945-8932
DOI:10.2500/ajra.2011.25.3672