Long-Term Outcome in Patients with Primary Hyperparathyroidism who Underwent Minimally Invasive Parathyroidectomy

Background Minimally invasive parathyroidectomy (MIP) has become a well-accepted treatment for selected patients with primary hyperparathyroidism (PHPT). However, few studies have evaluated long-term outcomes for this operative approach. We therefore chose to examine both the long-term symptom resol...

Full description

Saved in:
Bibliographic Details
Published in:World journal of surgery 2012-01, Vol.36 (1), p.55-60
Main Authors: Venkat, Raghunandan, Kouniavsky, Guennadi, Tufano, Ralph P., Schneider, Eric B., Dackiw, Alan P. B., Zeiger, Martha A.
Format: Article
Language:English
Subjects:
Abdominal Surgery
Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers - blood
Calcium - blood
Cardiac Surgery
Female
Follow-Up Studies
General Surgery
Humans
Hyperparathyroidism, Primary - blood
Hyperparathyroidism, Primary - diagnosis
Hyperparathyroidism, Primary - surgery
Male
Medicine
Medicine & Public Health
Middle Aged
Minimally Invasive Surgical Procedures
Parathyroid Adenoma
Parathyroid Carcinoma
Parathyroid Hormone - blood
Parathyroidectomy - methods
Primary Hyperparathyroidism
Reoperation
Retrospective Studies
Serum Calcium Level
Single Photon Emission Compute Tomography
Surgery
Surveys and Questionnaires
Thoracic Surgery
Treatment Outcome
Vascular Surgery
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Minimally invasive parathyroidectomy (MIP) has become a well-accepted treatment for selected patients with primary hyperparathyroidism (PHPT). However, few studies have evaluated long-term outcomes for this operative approach. We therefore chose to examine both the long-term symptom resolution and biochemical cure following MIP for PHPT. Methods A total of 460 PHPT patients who underwent a MIP between 2004 and 2009 were successfully mailed a questionnaire that assessed preoperative and postoperative Parathyroidectomy Assessment of Symptoms (PAS) scores, most recent calcium and parathyroid hormone (PTH) levels, and information about any reoperation for PHPT. Long-term evaluation of symptomatic and biochemical cure was performed. Results A total of 200 patients (43.5%) responded to our correspondence. The mean age of the patients was 58.7 ± 11.9 years, 74.5% were female, and 78.5% were Caucasian. The mean follow-up was 37 ± 19 months. The mean PAS scores fell by 117 ± 14 at long-term follow-up after MIP ( P  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-011-1344-8