Intra-lateral septal infusions of folic acid alone or combined with various antidepressant drugs produce antidepressant-like actions in male Wistar rats forced to swim

Intra-cerebral administrations of folic acid produce antidepressant-like effects; either alone or combined with several antidepressant drugs. However, the specific limbic structures implied in the antidepressant-like actions of folic acid are un-known. Thus, intra-lateral septal infusions of folic a...

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Bibliographic Details
Published in:Progress in neuro-psychopharmacology & biological psychiatry 2012-01, Vol.36 (1), p.78-84
Main Authors: Molina-Hernández, Miguel, Téllez-Alcántara, N. Patricia, Olivera-López, Jorge I., Jaramillo, M. Teresa
Format: Article
Language:English
Subjects:
Animals
Antidepressant
Antidepressive Agents - administration & dosage
Biological and medical sciences
Depression - drug therapy
Depression - psychology
Drug Therapy, Combination
Folic acid
Folic Acid - administration & dosage
Forced swimming test
Infusions, Intraventricular
Lateral septal nuclei
Male
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Rats
Rats, Wistar
Septum of Brain - drug effects
Septum of Brain - physiology
Swimming - psychology
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Summary:Intra-cerebral administrations of folic acid produce antidepressant-like effects; either alone or combined with several antidepressant drugs. However, the specific limbic structures implied in the antidepressant-like actions of folic acid are un-known. Thus, intra-lateral septal infusions of folic acid (5.0nmol, P
ISSN:0278-5846
1878-4216
DOI:10.1016/j.pnpbp.2011.08.020