Loading…
Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience
Abstract Osteoradionecrosis of the jaw remains the most problematic consequence of radiotherapy for the management of head and neck cancer. Treatment is often complex and multimodal. New theories on its pathophysiology have allowed the development of potential treatment modalities, including the use...
Saved in:
| Published in: | British journal of oral & maxillofacial surgery 2012-01, Vol.50 (1), p.41-44 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123 |
| container_end_page | 44 |
| container_issue | 1 |
| container_start_page | 41 |
| container_title | British journal of oral & maxillofacial surgery |
| container_volume | 50 |
| creator | Mcleod, N.M.H Pratt, C.A Mellor, T.K Brennan, P.A |
| description | Abstract Osteoradionecrosis of the jaw remains the most problematic consequence of radiotherapy for the management of head and neck cancer. Treatment is often complex and multimodal. New theories on its pathophysiology have allowed the development of potential treatment modalities, including the use of pentoxifylline and tocopherol. In this retrospective case series we examined the outcomes of patients with ORN prescribed pentoxifylline and tocopherol. |
| doi_str_mv | 10.1016/j.bjoms.2010.11.017 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_913439852</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0266435610003827</els_id><sourcerecordid>913439852</sourcerecordid><originalsourceid>FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123</originalsourceid><addsrcrecordid>eNqFkU9v1DAQxS0EokvhEyAh37iQrcdOnPgAEqr4J1VqpcLZ8joT1iGJg-1A99vj7BYOvXDyyH5vPPN7hLwEtgUG8qLf7no_xi1n6w1sGdSPyAYqwQtQJXtMNoxLWZSikmfkWYw9Y6ziUD0lZxx4WcsaNmS6wSn5O9cdhsFNSM3U0uStn_cY_EDdRNMe6Wgm8x3HLKW-o7NJLpeR_nZpT31M6INpnZ_QBh9dfHP03PiQ4uiXLMG7GUO2WHxOnnRmiPji_jwn3z5--Hr5ubi6_vTl8v1VYUsQqcB6V0vFVamMrE2DWDVlaysjGENl8uTG2toidCi5UCw_SwVMNjvFbMmAi3Py-tR3Dv7ngjHp0UWLw2Am9EvUCkQpVFOtSnFSrrPHgJ2egxtNOGhgeuWse33krFfOGkBnztn16r7_shux_ef5CzYL3p4EmLf85TDoaI8EWhfQJt16958P3j3w25yPs2b4gQeMvV_ClAFq0JFrpm_XqNekIYcsGl6LPyexpnA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>913439852</pqid></control><display><type>article</type><title>Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience</title><source>ScienceDirect Journals</source><creator>Mcleod, N.M.H ; Pratt, C.A ; Mellor, T.K ; Brennan, P.A</creator><creatorcontrib>Mcleod, N.M.H ; Pratt, C.A ; Mellor, T.K ; Brennan, P.A</creatorcontrib><description>Abstract Osteoradionecrosis of the jaw remains the most problematic consequence of radiotherapy for the management of head and neck cancer. Treatment is often complex and multimodal. New theories on its pathophysiology have allowed the development of potential treatment modalities, including the use of pentoxifylline and tocopherol. In this retrospective case series we examined the outcomes of patients with ORN prescribed pentoxifylline and tocopherol.</description><identifier>ISSN: 0266-4356</identifier><identifier>EISSN: 1532-1940</identifier><identifier>DOI: 10.1016/j.bjoms.2010.11.017</identifier><identifier>PMID: 21247671</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Aged ; Antioxidants - administration & dosage ; Antioxidants - therapeutic use ; Dentistry ; Female ; Follow-Up Studies ; Humans ; Jaw Diseases - classification ; Jaw Diseases - drug therapy ; Male ; Middle Aged ; Mouth Neoplasms - radiotherapy ; Neoadjuvant Therapy ; Oropharyngeal Neoplasms - radiotherapy ; Osteoradionecrosis - classification ; Osteoradionecrosis - drug therapy ; Pentoxifylline - administration & dosage ; Pentoxifylline - therapeutic use ; Pentoxifylline, Tocopherol, Osteoradionecrosis, Jaw ; Radiation-Protective Agents - administration & dosage ; Radiation-Protective Agents - therapeutic use ; Retrospective Studies ; Surgery ; Tocopherols - administration & dosage ; Tocopherols - therapeutic use ; Tongue Neoplasms - radiotherapy ; Treatment Outcome</subject><ispartof>British journal of oral & maxillofacial surgery, 2012-01, Vol.50 (1), p.41-44</ispartof><rights>The British Association of Oral and Maxillofacial Surgeons</rights><rights>2010 The British Association of Oral and Maxillofacial Surgeons</rights><rights>Copyright © 2010 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123</citedby><cites>FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21247671$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mcleod, N.M.H</creatorcontrib><creatorcontrib>Pratt, C.A</creatorcontrib><creatorcontrib>Mellor, T.K</creatorcontrib><creatorcontrib>Brennan, P.A</creatorcontrib><title>Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience</title><title>British journal of oral & maxillofacial surgery</title><addtitle>Br J Oral Maxillofac Surg</addtitle><description>Abstract Osteoradionecrosis of the jaw remains the most problematic consequence of radiotherapy for the management of head and neck cancer. Treatment is often complex and multimodal. New theories on its pathophysiology have allowed the development of potential treatment modalities, including the use of pentoxifylline and tocopherol. In this retrospective case series we examined the outcomes of patients with ORN prescribed pentoxifylline and tocopherol.</description><subject>Aged</subject><subject>Antioxidants - administration & dosage</subject><subject>Antioxidants - therapeutic use</subject><subject>Dentistry</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Jaw Diseases - classification</subject><subject>Jaw Diseases - drug therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mouth Neoplasms - radiotherapy</subject><subject>Neoadjuvant Therapy</subject><subject>Oropharyngeal Neoplasms - radiotherapy</subject><subject>Osteoradionecrosis - classification</subject><subject>Osteoradionecrosis - drug therapy</subject><subject>Pentoxifylline - administration & dosage</subject><subject>Pentoxifylline - therapeutic use</subject><subject>Pentoxifylline, Tocopherol, Osteoradionecrosis, Jaw</subject><subject>Radiation-Protective Agents - administration & dosage</subject><subject>Radiation-Protective Agents - therapeutic use</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Tocopherols - administration & dosage</subject><subject>Tocopherols - therapeutic use</subject><subject>Tongue Neoplasms - radiotherapy</subject><subject>Treatment Outcome</subject><issn>0266-4356</issn><issn>1532-1940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqFkU9v1DAQxS0EokvhEyAh37iQrcdOnPgAEqr4J1VqpcLZ8joT1iGJg-1A99vj7BYOvXDyyH5vPPN7hLwEtgUG8qLf7no_xi1n6w1sGdSPyAYqwQtQJXtMNoxLWZSikmfkWYw9Y6ziUD0lZxx4WcsaNmS6wSn5O9cdhsFNSM3U0uStn_cY_EDdRNMe6Wgm8x3HLKW-o7NJLpeR_nZpT31M6INpnZ_QBh9dfHP03PiQ4uiXLMG7GUO2WHxOnnRmiPji_jwn3z5--Hr5ubi6_vTl8v1VYUsQqcB6V0vFVamMrE2DWDVlaysjGENl8uTG2toidCi5UCw_SwVMNjvFbMmAi3Py-tR3Dv7ngjHp0UWLw2Am9EvUCkQpVFOtSnFSrrPHgJ2egxtNOGhgeuWse33krFfOGkBnztn16r7_shux_ef5CzYL3p4EmLf85TDoaI8EWhfQJt16958P3j3w25yPs2b4gQeMvV_ClAFq0JFrpm_XqNekIYcsGl6LPyexpnA</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Mcleod, N.M.H</creator><creator>Pratt, C.A</creator><creator>Mellor, T.K</creator><creator>Brennan, P.A</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120101</creationdate><title>Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience</title><author>Mcleod, N.M.H ; Pratt, C.A ; Mellor, T.K ; Brennan, P.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Antioxidants - administration & dosage</topic><topic>Antioxidants - therapeutic use</topic><topic>Dentistry</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Jaw Diseases - classification</topic><topic>Jaw Diseases - drug therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mouth Neoplasms - radiotherapy</topic><topic>Neoadjuvant Therapy</topic><topic>Oropharyngeal Neoplasms - radiotherapy</topic><topic>Osteoradionecrosis - classification</topic><topic>Osteoradionecrosis - drug therapy</topic><topic>Pentoxifylline - administration & dosage</topic><topic>Pentoxifylline - therapeutic use</topic><topic>Pentoxifylline, Tocopherol, Osteoradionecrosis, Jaw</topic><topic>Radiation-Protective Agents - administration & dosage</topic><topic>Radiation-Protective Agents - therapeutic use</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Tocopherols - administration & dosage</topic><topic>Tocopherols - therapeutic use</topic><topic>Tongue Neoplasms - radiotherapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mcleod, N.M.H</creatorcontrib><creatorcontrib>Pratt, C.A</creatorcontrib><creatorcontrib>Mellor, T.K</creatorcontrib><creatorcontrib>Brennan, P.A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of oral & maxillofacial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mcleod, N.M.H</au><au>Pratt, C.A</au><au>Mellor, T.K</au><au>Brennan, P.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience</atitle><jtitle>British journal of oral & maxillofacial surgery</jtitle><addtitle>Br J Oral Maxillofac Surg</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>50</volume><issue>1</issue><spage>41</spage><epage>44</epage><pages>41-44</pages><issn>0266-4356</issn><eissn>1532-1940</eissn><abstract>Abstract Osteoradionecrosis of the jaw remains the most problematic consequence of radiotherapy for the management of head and neck cancer. Treatment is often complex and multimodal. New theories on its pathophysiology have allowed the development of potential treatment modalities, including the use of pentoxifylline and tocopherol. In this retrospective case series we examined the outcomes of patients with ORN prescribed pentoxifylline and tocopherol.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>21247671</pmid><doi>10.1016/j.bjoms.2010.11.017</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0266-4356 |
| ispartof | British journal of oral & maxillofacial surgery, 2012-01, Vol.50 (1), p.41-44 |
| issn | 0266-4356 1532-1940 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_913439852 |
| source | ScienceDirect Journals |
| subjects | Aged Antioxidants - administration & dosage Antioxidants - therapeutic use Dentistry Female Follow-Up Studies Humans Jaw Diseases - classification Jaw Diseases - drug therapy Male Middle Aged Mouth Neoplasms - radiotherapy Neoadjuvant Therapy Oropharyngeal Neoplasms - radiotherapy Osteoradionecrosis - classification Osteoradionecrosis - drug therapy Pentoxifylline - administration & dosage Pentoxifylline - therapeutic use Pentoxifylline, Tocopherol, Osteoradionecrosis, Jaw Radiation-Protective Agents - administration & dosage Radiation-Protective Agents - therapeutic use Retrospective Studies Surgery Tocopherols - administration & dosage Tocopherols - therapeutic use Tongue Neoplasms - radiotherapy Treatment Outcome |
| title | Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T02%3A41%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pentoxifylline%20and%20tocopherol%20in%20the%20management%20of%20patients%20with%20osteoradionecrosis,%20the%20Portsmouth%20experience&rft.jtitle=British%20journal%20of%20oral%20&%20maxillofacial%20surgery&rft.au=Mcleod,%20N.M.H&rft.date=2012-01-01&rft.volume=50&rft.issue=1&rft.spage=41&rft.epage=44&rft.pages=41-44&rft.issn=0266-4356&rft.eissn=1532-1940&rft_id=info:doi/10.1016/j.bjoms.2010.11.017&rft_dat=%3Cproquest_cross%3E913439852%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c413t-e7b7692949a67a8ee584dc5a300e9a767acc7ce1fe62390e58691068b90c40123%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=913439852&rft_id=info:pmid/21247671&rfr_iscdi=true |