High resolution MRI of the breast at 3 T: which BI-RADS® descriptors are most strongly associated with the diagnosis of breast cancer?

Objective To identify which breast lesion descriptors in the ACR BI-RADS® MRI lexicon are most strongly associated with the diagnosis of breast cancer when performing breast MR imaging at 3 T. Methods 150 patients underwent breast MR imaging at 3 T. Lesion size, morphology and enhancement kinetics w...

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Bibliographic Details
Published in:European radiology 2012-02, Vol.22 (2), p.322-330
Main Authors: Pinker-Domenig, K., Bogner, W., Gruber, S., Bickel, H., Duffy, S., Schernthaner, M., Dubsky, P., Pluschnig, U., Rudas, M., Trattnig, S., Helbich, T. H.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Breast
Breast - pathology
Breast cancer
Breast Neoplasms - diagnosis
Breast Neoplasms - pathology
Contrast Media - pharmacology
Diagnostic Radiology
Female
Humans
Image Processing, Computer-Assisted
Imaging
Internal Medicine
Interventional Radiology
Kinetics
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Medical Oncology - methods
Medicine
Medicine & Public Health
Middle Aged
Morphology
Neuroradiology
Preventive medicine
Radiology
Regression Analysis
Reproducibility of Results
Sensitivity and Specificity
Ultrasound
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Summary:Objective To identify which breast lesion descriptors in the ACR BI-RADS® MRI lexicon are most strongly associated with the diagnosis of breast cancer when performing breast MR imaging at 3 T. Methods 150 patients underwent breast MR imaging at 3 T. Lesion size, morphology and enhancement kinetics were assessed according to the BI-RADS® classification. Sensitivity, specificity and diagnostic accuracy were assessed. The effects of the BI-RADS® descriptors on sensitivity and specificity were evaluated. Data were analysed using logistic regression. Histopathological diagnoses were used as the standard of reference. Results The sensitivity, specificity and diagnostic accuracy of breast MRI at 3 T was 99%, 81% and 93%, respectively. In univariate analysis, the final diagnosis of malignancy was positively associated with irregular shape ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-011-2256-6