Elderly cases of Churg–Strauss syndrome: Case report and review of Japanese cases

Churg–Strauss syndrome (CSS) is a vasculitis usually thought to affect comparatively young individuals, however, elderly cases of CSS are being reported increasingly. We report two elderly cases of CSS and review 123 cases of CSS reported in Japan between 2003 and 2010. The two patients showed typic...

Full description

Saved in:
Bibliographic Details
Published in:Journal of dermatology 2012-01, Vol.39 (1), p.76-79
Main Authors: UCHIYAMA, Masaki, MITSUHASHI, Yoshihiko, YAMAZAKI, Masashi, TSUBOI, Ryoji
Format: Article
Language:English
Subjects:
Age of Onset
Aged
allergic granulomatous angiitis
Asian Continental Ancestry Group
Churg-Strauss Syndrome - complications
Churg-Strauss Syndrome - diagnosis
Churg–Strauss syndrome
elderly cases
eosinophilia
Female
Humans
Japan
Middle Aged
Nose
vasculitis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Churg–Strauss syndrome (CSS) is a vasculitis usually thought to affect comparatively young individuals, however, elderly cases of CSS are being reported increasingly. We report two elderly cases of CSS and review 123 cases of CSS reported in Japan between 2003 and 2010. The two patients showed typical features of CSS such as asthma, chronic sinusitis, purpura and mononeuritis multiplex. The biopsy specimens demonstrated leukocytoclastic vasculitis with infiltration of eosinophils. Both patients responded well to oral prednisolone. The age of the CSS cases we reviewed ranged from the teens to the 80s, with 47.2% of the patients aged 60 years or older. These patients tended more frequently to have complications such as gastrointestinal involvement, and a higher mortality rate. Elderly cases of CSS are not rare. Correct diagnosis at an earlier stage and careful, long‐term follow up are of particular importance in preventing a fatal outcome.
ISSN:0385-2407
1346-8138
DOI:10.1111/j.1346-8138.2011.01316.x