Value of gastrin-17 in detecting antral atrophy

Decreased plasma gastrin-17 (G-17), particularly after protein stimulation, is indicative of atrophy in the antral stomach mucosa. Available data on the value of this biomarker is inconclusive. Our study was aimed to evaluate the performance of the G-17 test in Caucasian and Asian patients for antra...

Full description

Saved in:
Bibliographic Details
Published in:Advances in medical sciences 2011-12, Vol.56 (2), p.145-150
Main Authors: Leja, M, Kupcinskas, L, Funka, K, Sudraba, A, Jonaitis, L, Ivanauskas, A, Janciauskas, D, Kuidelis, G, Chiu, HM, Lin, JT
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
atrophic gastritis
Atrophy
biomarkers
Biomarkers, Tumor - metabolism
diagnosis
Dietary Proteins
Female
Gastric Mucosa - metabolism
gastrin-17
Gastrins - blood
Gastritis, Atrophic - blood
Gastritis, Atrophic - diagnosis
Humans
Male
Middle Aged
Predictive Value of Tests
Reproducibility of Results
Sensitivity and Specificity
Stomach - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Decreased plasma gastrin-17 (G-17), particularly after protein stimulation, is indicative of atrophy in the antral stomach mucosa. Available data on the value of this biomarker is inconclusive. Our study was aimed to evaluate the performance of the G-17 test in Caucasian and Asian patients for antral atrophy evaluation either in fasting state or after protein stimulation. 241 dyspeptic patients aged 55 and above from Latvia (125), Lithuania (76) and Taiwan (40) were enrolled. G-17 levels were detected in plasma samples obtained either during fasting or after a protein-rich test meal. Levels
ISSN:1896-1126
1898-4002
DOI:10.2478/v10039-011-0040-0