Time course responses of serum GH, insulin, IGF-1, IGFBP1, and IGFBP3 concentrations after heavy resistance exercise in trained and untrained men

• Published in: Endocrine 2012-02, Vol.41 (1), p.144-151
• Main Authors: Hasani-Ranjbar, Shirin, Soleymani Far, Ehsan, Heshmat, Ramin, Rajabi, Hamid, Kosari, Hassan
• Format: Article
• Language: English
• Subjects: Adult; Body Mass Index; Diabetes; Endocrinology; Growth Hormone - blood; Humanities and Social Sciences; Humans; Insulin - blood; Insulin-Like Growth Factor Binding Protein 1 - blood; Insulin-Like Growth Factor Binding Protein 3 - blood; Insulin-Like Growth Factor I - metabolism; Internal Medicine; Life Style; Male; Medicine; Medicine & Public Health; multidisciplinary; Original Article; Physical Exertion - physiology; Physical Fitness - physiology; Resistance Training; Science; Surveys and Questionnaires; Time Factors
• ISSN: 1355-008X; 1559-0100
• DOI: 10.1007/s12020-011-9537-3

To investigate the effect of heavy resistance exercise on IGF-1 system, 19 healthy trained men and 15 healthy untrained men volunteered to participate in this study. The subjects were randomly divided into experimental and control groups. Subjects of experimental groups were forced to perform a heavy resistance exercise with the intensity of 70–80% of 1RM in selected movements. The blood samples were taken from all subjects four times; before (T1), immediately after (T2), 5 (T3), and 8 (T4) hours after exercise. Analysis of data showed that a session of heavy resistance exercise induced significant increase in GH at T2 ( P