Production of Late IFN-α Induced by Plasma γ-Globulin Fraction Proteins and Their Metal Complexes

Plasma γ-globulin fraction proteins, copper and zinc cations, and metal complexes they form with human serum γ-globulin induce the production of IFN-α by human blood cells throughout the periods of up to 72 h. Zinc cation-modified protein by 1.6 times ( p

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2011-04, Vol.150 (6), p.722-724
Main Authors: Cheknev, S. B., Babajanz, A. A., Efremova, I. E., Piskovskaya, L. S.
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cells, Cultured
Coordination Complexes - pharmacology
Copper - blood
Copper - metabolism
gamma-Globulins - metabolism
gamma-Globulins - pharmacology
Humans
Immunology and Microbiology
Interferon
Interferon-alpha - biosynthesis
Internal Medicine
Laboratory Medicine
Pathology
Physiological aspects
Zinc - blood
Zinc - metabolism
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Description
Summary:Plasma γ-globulin fraction proteins, copper and zinc cations, and metal complexes they form with human serum γ-globulin induce the production of IFN-α by human blood cells throughout the periods of up to 72 h. Zinc cation-modified protein by 1.6 times ( p
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1233-z