Common Regularities in Changes of the Neutrophil Functional Activity during In Vivo Growth of Tumors of Different Immunogenic Activity

Studies on BALB/c mice with tumors of different immunogenic activity (nonimmunogenic J774, WEHI 164 and immunogenic NS0) have showed that the development of a tumor is associated with changes in the neutrophil morphology and functions: the counts and size of the cells migrating to the focus increase...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2011-03, Vol.150 (5), p.590-593
Main Authors: Mal’tseva, V. N., Avkhacheva, N. V., Safronova, V. G.
Format: Article
Language:English
Subjects:
Active oxygen
Animals
Biomedical and Life Sciences
Biomedicine
Biophysics and Biochemistry
Cell Biology
Cell migration
Cell Movement
Cell Proliferation
Development and progression
Growth
Immune response
Immunogenicity
Internal Medicine
Laboratory Medicine
Leukocytes (neutrophilic)
Male
Mice
Mice, Inbred BALB C
Neoplasms, Experimental - immunology
Neutrophils - metabolism
Oxygen
Pathology
Reactive Oxygen Species - metabolism
Tumors
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Summary:Studies on BALB/c mice with tumors of different immunogenic activity (nonimmunogenic J774, WEHI 164 and immunogenic NS0) have showed that the development of a tumor is associated with changes in the neutrophil morphology and functions: the counts and size of the cells migrating to the focus increase and their capacity to produce active oxygen species is changed.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1198-y