Measurement of salivary resistin, visfatin and adiponectin levels

► Hormonal determination in saliva offers several advantages. ► We introduced a method for measuring resistin, visfatin and adiponectin in saliva. ► Salivary resistin and adiponectin significantly correlated with serum levels. ► No significant correlation between serum and salivary visfatin levels w...

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Bibliographic Details
Published in:Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2012-01, Vol.33 (1), p.120-124
Main Authors: Mamali, Irene, Roupas, Nikolaos D., Armeni, Anastasia K., Theodoropoulou, Anastasia, Markou, Kostas B., Georgopoulos, Neoklis A.
Format: Article
Language:English
Subjects:
active transport
Adipokines
Adiponectin
Adiponectin - analysis
Adiponectin - blood
Adipose Tissue
Adult
adults
blood serum
Body Mass Index
Correlation analysis
Cytokines - analysis
energy
enzyme immunoassays
Enzymes
Female
females
Humans
inflammation
insulin resistance
Male
males
Middle Aged
nicotinamide phosphoribosyltransferase
Nicotinamide Phosphoribosyltransferase - analysis
obesity
Peptides
Physiology
Reproduction
Resistin
Resistin - analysis
Resistin - blood
Saliva
Saliva - chemistry
Salivary glands
Serums
stress response
Visfatin
volunteers
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Summary:► Hormonal determination in saliva offers several advantages. ► We introduced a method for measuring resistin, visfatin and adiponectin in saliva. ► Salivary resistin and adiponectin significantly correlated with serum levels. ► No significant correlation between serum and salivary visfatin levels was observed. ► The determination of adipokines in saliva could be useful in clinical research. Hormonal determination in saliva offers several advantages. Peptides enter the salivary glands either by active transport mechanisms or are expressed and secreted by the salivary glands themselves. The collection of saliva is a noninvasive, easily repeatable and less stressful technique than blood withdrawal. The purpose of the present study was to introduce a method for measuring salivary resistin, visfatin and adiponectin levels and to evaluate their associations with serum levels. Resistin, visfatin and adiponectin levels were measured in serum and saliva of 50 healthy adult volunteers (17 male and 33 female) using commercial enzyme immunoassay kits for serum with minor modifications. The present study documented the determination of resistin and adiponectin levels in saliva and the significant correlation of salivary levels with serum levels (r=0.441, p
ISSN:0196-9781
1873-5169
DOI:10.1016/j.peptides.2011.11.007