Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: Developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV

• Published in: Journal of controlled release 2011-11, Vol.152, p.e9-e10
• Main Authors: Choi, Sunmi, Lee, Jangwook, Kumar, Priti, Lee, Kuen Yong, Lee, Sang-Kyung
• Format: Article
• Language: English
• Subjects: Anti-HIV Agents - chemistry; Anti-HIV Agents - metabolism; Anti-HIV Agents - pharmacology; Anti-HIV Agents - toxicity; Antigens, CD7 - immunology; Cell Line; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flow Cytometry; Histone Deacetylase Inhibitors - chemistry; Histone Deacetylase Inhibitors - metabolism; Histone Deacetylase Inhibitors - pharmacology; Histone Deacetylase Inhibitors - toxicity; HIV - drug effects; HIV - physiology; Humans; Immunoconjugates - chemistry; Immunoconjugates - metabolism; Immunoconjugates - pharmacology; Immunoconjugates - toxicity; Lactic Acid - chemistry; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Particle Size; Polyglycolic Acid - chemistry; Single-Chain Antibodies - chemistry; Single-Chain Antibodies - metabolism; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; T-Lymphocytes - virology; Technology, Pharmaceutical - methods; Virus Latency
• ISSN: 0168-3659; 1873-4995
• DOI: 10.1016/j.jconrel.2011.08.089