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Clinical pulmonary infection score to diagnose ventilator-associated pneumonia in children

Background There is a need to validate and suggest easy clinical method for diagnosis of ventilator-associated pneumonia (VAP) in developing countries. Objectives To validate the use of simplified Clinical Pulmonary Infection Score (CPIS) for the diagnosis of VAP. Design Prospective study. Setting P...

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Bibliographic Details
Published in:Indian pediatrics 2011-12, Vol.48 (12), p.949-954
Main Authors: Sachdev, Anil, Chugh, K., Sethi, M., Gupta, D., Wattal, C., Menon, G.
Format: Article
Language:English
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Summary:Background There is a need to validate and suggest easy clinical method for diagnosis of ventilator-associated pneumonia (VAP) in developing countries. Objectives To validate the use of simplified Clinical Pulmonary Infection Score (CPIS) for the diagnosis of VAP. Design Prospective study. Setting Pediatric intensive care unit of a tertiary care teaching hospital. Subjects 30 children receiving mechanical ventilation for more than 48 hours and with simplified CPIS≥6. Methods All patients underwent flexible bronchoscopy to obtain bronchoalveolar lavage which was analyzed quantitatively. Colony count ≥10 4 cfu/mL was considered reference standard for definite VAP. Results Of the five variables used for simplified CPIS, only patient’s temperature ( P =0.013) and PaO 2 /FiO 2 ratio were significant ( P
ISSN:0019-6061
0974-7559
DOI:10.1007/s13312-011-0154-2