Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice

• Published in: Hepatobiliary & pancreatic diseases international 2012-02, Vol.11 (1), p.81-88
• Main Authors: Fan, Chao, Yan, Xiao-Peng, Liu, Shi-Qi, Wang, Chun-Bao, Li, Jian-Hui, Yu, Liang, Wu, Zheng, Lv, Yi
• Format: Article
• Language: English
• Subjects: anastomats; anastomosis, Roux-en-Y; Anastomosis, Roux-en-Y - adverse effects; Anastomosis, Roux-en-Y - instrumentation; Animals; Bilirubin - blood; Biomarkers - blood; choledochostomy; Choledochostomy - adverse effects; Choledochostomy - instrumentation; compressive; Disease Models, Animal; Dogs; Endocrinology & Metabolism; Equipment Design; Gastroenterology and Hepatology; jaundice, obstructive; Jaundice, Obstructive - blood; Jaundice, Obstructive - surgery; magnetic; magnetic compressive anastomats; Magnetics - instrumentation; Male; Surgical Equipment; Time Factors
• ISSN: 1499-3872
• DOI: 10.1016/S1499-3872(11)60129-X

BACKGROUND:The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated,and the incidence of postoperative complications has remained high.A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.METHODS:After ligating the common bile duct for 7 days,16 dogs were randomly divided into two groups (n=8 per group).Anastomats were used in the study group,and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy.We compared the operation time,incidence of complications,gross appearance,and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.RESULTS:The time spent on constructing the anastomosis for the study group was significantly shortened.Although no anastomotic stenosis occurred in the two groups,the narrowing rate of biliary-enteric anastomosis was much higher in the control group.There was one case of bile leakage in the control group,whereas no bile leakage occurred in the study group.A smoother surface,an improved layer apposition,and a lower local inflammatory response were identified in the anastomosis of the study group.CONCLUSION:The structures of the novel magnetic compressive anastomats are simple,and they are time-saving,safe and efficient for performing Roux-en-Y choledocho- jejunostomy procedures in a canine model of obstructive jaundice.