Cold intermittent cardioplegia reduces the acidosis during prolonged cardiac surgery with cardiopulmonary bypass

The effect on acid-base balance efficacy of intermittent warm and cold blood cardioplegia (IWBC, ICBC) was assessed in 44 patients who underwent cardiac surgery with prolonged aortic cross clamping. With this purpose a customized multi sensor probe was inserted in the coronary sinus, and pH, PO 2 ,...

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Bibliographic Details
Main Authors: Nollo, G., Ferrari, P., Graffigna, A. C.
Format: Conference Proceeding
Language:English
Subjects:
Blood
Heart
Monitoring
Myocardium
Probes
Surgery
Temperature measurement
Online Access:Request full text
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Summary:The effect on acid-base balance efficacy of intermittent warm and cold blood cardioplegia (IWBC, ICBC) was assessed in 44 patients who underwent cardiac surgery with prolonged aortic cross clamping. With this purpose a customized multi sensor probe was inserted in the coronary sinus, and pH, PO 2 , PCO 2 and temperature were continuously measured at 1 Hz sampling rate. The mean cross-clamping time was of 76 ± 26 min on 19 IWBC cases and of 80 ± 24 min on 14 ICBC cases. With IWBC perfusion, at the end of every ischemic period, the lowest pH and PO 2 progressively decreased and the maximal PCO 2 increased. During ICBC the minimum of pH and PO 2 and maximum of PCO2 at the end of different ischemic period during time were constant, also during long cross-clamping time. With IWBC, myocardial ischemia seemed not completely reversed by standardized reperfusions, as reflected by steady deterioration of PCO 2 and pH after each reperfusion.
ISSN:1094-687X
1558-4615
2694-0604
DOI:10.1109/IEMBS.2011.6092080